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- W142260586 abstract "The objective of these studies was to measure the effect of orally administered cinnamon on glucose tolerance and insulin secretion in vivo. Young male Wistar rats were rendered diabetic by intravenous administration of streptozotocin (40 mg/Kg body weight) in order to produce animals with Type 2 diabetic characteristics. After a two week period of stabilization, oral glucose tolerance tests were performed tri-iweekly and blood samples were collected at 0, 15, 30, 60 & 90 minutes post-glucose for glucose and insulin analyses. Glucose and insulin responses in rats given ground cinnamon added to the glucose test solution were compared with responses in diabetic control rats given glucose test solution only. The observations indicated that acute cinnamon dosing causes a marked improvement of impaired glucose tolerance accompanied by significant increases in rates of insulin secretion in this diabetic animal model. Thus, in addition to its documented effects on peripheral tissue insulin sensitivity, the data shown here indicates that cinnamon dosing also has beneficial effects on functioning of the endocrine pancreas. Support was from USDA ARS & Phytomed, Inc." @default.
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- W142260586 date "2007-01-01" @default.
- W142260586 modified "2023-09-25" @default.
- W142260586 title "Cinnamon Administration Enhances Glucose‐Induced Insulin Secretion in Diabetic Rats." @default.
- W142260586 doi "https://doi.org/10.1096/fasebj.21.6.a1085-c" @default.
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