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• W1422765340 abstract "This chapter focuses on magnocellular neurons. There are two major groups of large neurosecretory neurons in the hypothalamus: one in the supraoptic nucleus (SON) and the other in the paraventricular nucleus (PVN). The magnocellular neurons develop from midline neuroblasts. Those in the SON migrate ventrolaterally and take up residence alongside the optic chiasm. The scattered nests of cells fail to complete this migration and come to rest between the PVN and SON. These nests of neurons are called “accessory magnocellular cells” and make up less than 5% of the magnocellular population. The chapter demonstrates the presence or absence of particular transmitters in magnocellular cells. The studies of the effect of stalk transections or PVN lesions on transmitter levels in the posterior pituitary have helped to show whether neurotransmitters are in non-neuronal cells intrinsic to the posterior lobe or in processes provided by neurons extrinsic to it. The various magnocellular neurons make vasopressin—the antidiuretic hormone—or oxytocin—the hormone responsible for milk letdown." @default.
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• W1422765340 date "1986-01-01" @default.
• W1422765340 modified "2023-09-27" @default.
• W1422765340 title "Chapter 11 Multiple chemical messengers in hypothalamic magnocellular neurons" @default.
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• W1422765340 doi "https://doi.org/10.1016/s0079-6123(08)60237-x" @default.
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