Matches in SemOpenAlex for { <https://semopenalex.org/work/W142487709> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W142487709 endingPage "99" @default.
- W142487709 startingPage "77" @default.
- W142487709 abstract "Radioimmunotherapy (RIT) is one aspect of a more general therapeutic approach which involves the biological targeting of ionising radiation to tumours. The distinguishing feature of RIT is the use of immunologically based targeting molecules such as antibodies and their fragments. Some useful and encouraging clinical results have been achieved with antibody-targeted therapy (Press et al. 1993; Hird et al. 1993; Riva et al. 1994). There are, however, other possible molecules which may be used for tumour targeting. One of the most promising of these is meta-iodobenzylguanidine (mIBG) which has certain structural similarities to noradrenaline. This agent is in clinical use for the biologically targeted radiotherapy of neuroblastoma and phaeochromocytoma (Voute et al. 1991; Lashford et al. 1992). In the future it is very likely that other classes of targeting molecule will also find application for tumour targeting. Which class of radionuclide to use depends on the manner in which the targeting molecule becomes associated with the targeted tumour cell. At present radionuclides which emit β-particles are used to the virtual exclusion of all others, although the potential of α-emitting radionuclides is also being explored (Junghans et al. 1993; Vaidyanathan and Zalutsky 1992). These are reasonable choices if the targeting molecule is bound to the cell surface or internalised to non-nuclear regions." @default.
- W142487709 created "2016-06-24" @default.
- W142487709 creator A5039475847 @default.
- W142487709 date "1996-01-01" @default.
- W142487709 modified "2023-10-17" @default.
- W142487709 title "Optimal Therapeutic Strategies for Radioimmunotherapy" @default.
- W142487709 cites W1963613808 @default.
- W142487709 cites W1970405229 @default.
- W142487709 cites W1971747664 @default.
- W142487709 cites W1986478975 @default.
- W142487709 cites W1994524105 @default.
- W142487709 cites W1999805371 @default.
- W142487709 cites W2001054460 @default.
- W142487709 cites W2006293829 @default.
- W142487709 cites W2011675379 @default.
- W142487709 cites W2018195788 @default.
- W142487709 cites W2029517266 @default.
- W142487709 cites W2031822911 @default.
- W142487709 cites W2050096691 @default.
- W142487709 cites W2051695868 @default.
- W142487709 cites W2086439980 @default.
- W142487709 cites W2107504931 @default.
- W142487709 cites W2166406736 @default.
- W142487709 cites W2320751441 @default.
- W142487709 doi "https://doi.org/10.1007/978-3-642-79952-5_6" @default.
- W142487709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8722421" @default.
- W142487709 hasPublicationYear "1996" @default.
- W142487709 type Work @default.
- W142487709 sameAs 142487709 @default.
- W142487709 citedByCount "16" @default.
- W142487709 countsByYear W1424877092019 @default.
- W142487709 crossrefType "book-chapter" @default.
- W142487709 hasAuthorship W142487709A5039475847 @default.
- W142487709 hasConcept C121608353 @default.
- W142487709 hasConcept C126322002 @default.
- W142487709 hasConcept C159654299 @default.
- W142487709 hasConcept C185592680 @default.
- W142487709 hasConcept C203014093 @default.
- W142487709 hasConcept C2776146153 @default.
- W142487709 hasConcept C2776715637 @default.
- W142487709 hasConcept C2781230642 @default.
- W142487709 hasConcept C2989005 @default.
- W142487709 hasConcept C2993559085 @default.
- W142487709 hasConcept C502942594 @default.
- W142487709 hasConcept C509974204 @default.
- W142487709 hasConcept C542903549 @default.
- W142487709 hasConcept C54355233 @default.
- W142487709 hasConcept C70721500 @default.
- W142487709 hasConcept C71924100 @default.
- W142487709 hasConcept C81885089 @default.
- W142487709 hasConcept C86803240 @default.
- W142487709 hasConceptScore W142487709C121608353 @default.
- W142487709 hasConceptScore W142487709C126322002 @default.
- W142487709 hasConceptScore W142487709C159654299 @default.
- W142487709 hasConceptScore W142487709C185592680 @default.
- W142487709 hasConceptScore W142487709C203014093 @default.
- W142487709 hasConceptScore W142487709C2776146153 @default.
- W142487709 hasConceptScore W142487709C2776715637 @default.
- W142487709 hasConceptScore W142487709C2781230642 @default.
- W142487709 hasConceptScore W142487709C2989005 @default.
- W142487709 hasConceptScore W142487709C2993559085 @default.
- W142487709 hasConceptScore W142487709C502942594 @default.
- W142487709 hasConceptScore W142487709C509974204 @default.
- W142487709 hasConceptScore W142487709C542903549 @default.
- W142487709 hasConceptScore W142487709C54355233 @default.
- W142487709 hasConceptScore W142487709C70721500 @default.
- W142487709 hasConceptScore W142487709C71924100 @default.
- W142487709 hasConceptScore W142487709C81885089 @default.
- W142487709 hasConceptScore W142487709C86803240 @default.
- W142487709 hasLocation W1424877091 @default.
- W142487709 hasLocation W1424877092 @default.
- W142487709 hasOpenAccess W142487709 @default.
- W142487709 hasPrimaryLocation W1424877091 @default.
- W142487709 hasRelatedWork W1532568685 @default.
- W142487709 hasRelatedWork W1787597555 @default.
- W142487709 hasRelatedWork W2066978337 @default.
- W142487709 hasRelatedWork W2099970938 @default.
- W142487709 hasRelatedWork W2169294576 @default.
- W142487709 hasRelatedWork W2386398244 @default.
- W142487709 hasRelatedWork W2407024650 @default.
- W142487709 hasRelatedWork W3029990388 @default.
- W142487709 hasRelatedWork W3031189307 @default.
- W142487709 hasRelatedWork W4316362296 @default.
- W142487709 isParatext "false" @default.
- W142487709 isRetracted "false" @default.
- W142487709 magId "142487709" @default.
- W142487709 workType "book-chapter" @default.