Matches in SemOpenAlex for { <https://semopenalex.org/work/W1425694003> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1425694003 endingPage "8" @default.
- W1425694003 startingPage "1082" @default.
- W1425694003 abstract "The beta-amyloid peptide (beta AP) has been characterized by protein sequencing techniques as a 39-43 amino acid protein with heterogeneous COOH-termini. Controversy exists regarding the predominant form of beta AP in neuritic plaques (NP) and cerebral vasculature of Alzheimer's disease (AD) brain. A monoclonal antibody was developed that selectively recognizes the free COOH-terminal of beta AP 1-42 but not beta AP species with shorter or longer COOH-termini. Brain sections from AD and related disorders were examined using this antibody. In AD samples, the antibody stained diffuse amyloid and NP cores, many intraneuronal and extraneuronal neurofibrillary tangles (NFT), but not cerebrovascular amyloid. Pick and Lewy bodies lacked immunoreactivity. These findings suggest that beta AP 1-42 is present in early and mature amyloid deposits and NFT, but that species of beta AP other than 1-42 comprise human vascular deposits." @default.
- W1425694003 created "2016-06-24" @default.
- W1425694003 creator A5008607260 @default.
- W1425694003 creator A5023729567 @default.
- W1425694003 creator A5031835127 @default.
- W1425694003 creator A5033718619 @default.
- W1425694003 creator A5036294083 @default.
- W1425694003 creator A5077920561 @default.
- W1425694003 date "1994-05-01" @default.
- W1425694003 modified "2023-09-27" @default.
- W1425694003 title "Development of a monoclonal antibody specific for the COOH-terminal of beta-amyloid 1-42 and its immunohistochemical reactivity in Alzheimer's disease and related disorders." @default.
- W1425694003 cites W137525261 @default.
- W1425694003 cites W1516306407 @default.
- W1425694003 cites W1604272660 @default.
- W1425694003 cites W1688111961 @default.
- W1425694003 cites W1758831574 @default.
- W1425694003 cites W1977186252 @default.
- W1425694003 cites W1996645520 @default.
- W1425694003 cites W2013833879 @default.
- W1425694003 cites W2017643275 @default.
- W1425694003 cites W2029261819 @default.
- W1425694003 cites W2038701321 @default.
- W1425694003 cites W2059804089 @default.
- W1425694003 cites W2067811915 @default.
- W1425694003 cites W2071953900 @default.
- W1425694003 cites W2093899542 @default.
- W1425694003 cites W2108689038 @default.
- W1425694003 cites W2414246859 @default.
- W1425694003 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1887348" @default.
- W1425694003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8178931" @default.
- W1425694003 hasPublicationYear "1994" @default.
- W1425694003 type Work @default.
- W1425694003 sameAs 1425694003 @default.
- W1425694003 citedByCount "17" @default.
- W1425694003 crossrefType "journal-article" @default.
- W1425694003 hasAuthorship W1425694003A5008607260 @default.
- W1425694003 hasAuthorship W1425694003A5023729567 @default.
- W1425694003 hasAuthorship W1425694003A5031835127 @default.
- W1425694003 hasAuthorship W1425694003A5033718619 @default.
- W1425694003 hasAuthorship W1425694003A5036294083 @default.
- W1425694003 hasAuthorship W1425694003A5077920561 @default.
- W1425694003 hasConcept C142724271 @default.
- W1425694003 hasConcept C153911025 @default.
- W1425694003 hasConcept C159654299 @default.
- W1425694003 hasConcept C185592680 @default.
- W1425694003 hasConcept C199360897 @default.
- W1425694003 hasConcept C203014093 @default.
- W1425694003 hasConcept C204232928 @default.
- W1425694003 hasConcept C2776156579 @default.
- W1425694003 hasConcept C2776174256 @default.
- W1425694003 hasConcept C2777633098 @default.
- W1425694003 hasConcept C2779134260 @default.
- W1425694003 hasConcept C2779281246 @default.
- W1425694003 hasConcept C41008148 @default.
- W1425694003 hasConcept C502032728 @default.
- W1425694003 hasConcept C542903549 @default.
- W1425694003 hasConcept C55493867 @default.
- W1425694003 hasConcept C68026918 @default.
- W1425694003 hasConcept C71924100 @default.
- W1425694003 hasConcept C86803240 @default.
- W1425694003 hasConceptScore W1425694003C142724271 @default.
- W1425694003 hasConceptScore W1425694003C153911025 @default.
- W1425694003 hasConceptScore W1425694003C159654299 @default.
- W1425694003 hasConceptScore W1425694003C185592680 @default.
- W1425694003 hasConceptScore W1425694003C199360897 @default.
- W1425694003 hasConceptScore W1425694003C203014093 @default.
- W1425694003 hasConceptScore W1425694003C204232928 @default.
- W1425694003 hasConceptScore W1425694003C2776156579 @default.
- W1425694003 hasConceptScore W1425694003C2776174256 @default.
- W1425694003 hasConceptScore W1425694003C2777633098 @default.
- W1425694003 hasConceptScore W1425694003C2779134260 @default.
- W1425694003 hasConceptScore W1425694003C2779281246 @default.
- W1425694003 hasConceptScore W1425694003C41008148 @default.
- W1425694003 hasConceptScore W1425694003C502032728 @default.
- W1425694003 hasConceptScore W1425694003C542903549 @default.
- W1425694003 hasConceptScore W1425694003C55493867 @default.
- W1425694003 hasConceptScore W1425694003C68026918 @default.
- W1425694003 hasConceptScore W1425694003C71924100 @default.
- W1425694003 hasConceptScore W1425694003C86803240 @default.
- W1425694003 hasIssue "5" @default.
- W1425694003 hasLocation W14256940031 @default.
- W1425694003 hasOpenAccess W1425694003 @default.
- W1425694003 hasPrimaryLocation W14256940031 @default.
- W1425694003 hasRelatedWork W2010245335 @default.
- W1425694003 hasRelatedWork W2035380213 @default.
- W1425694003 hasRelatedWork W2045966187 @default.
- W1425694003 hasRelatedWork W2134804309 @default.
- W1425694003 hasRelatedWork W2336965499 @default.
- W1425694003 hasRelatedWork W2386985152 @default.
- W1425694003 hasRelatedWork W2410629327 @default.
- W1425694003 hasRelatedWork W2583402431 @default.
- W1425694003 hasRelatedWork W44439419 @default.
- W1425694003 hasRelatedWork W2005255342 @default.
- W1425694003 hasVolume "144" @default.
- W1425694003 isParatext "false" @default.
- W1425694003 isRetracted "false" @default.
- W1425694003 magId "1425694003" @default.
- W1425694003 workType "article" @default.