Matches in SemOpenAlex for { <https://semopenalex.org/work/W1427182169> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W1427182169 endingPage "198" @default.
- W1427182169 startingPage "193" @default.
- W1427182169 abstract "Cryptococcus neoformans is an opportunistic fungal pathogen that may lead to life-threatening meningoencephalitis and pulmonary infections in immunosuppressed hosts. The lack of an effective fungicidal regimen and the development of antifungal resistant strains suggest that continued investigation is necessary to devise immunotherapeutic strategies and/or drug targets to combat C. neoformans infections. Studies to date involve investigating the host-pathogen interaction of cryptococcal infections through the genetic manipulation of the yeast, as well as the characterization of the host immune response. Macrophage phagocytosis and killing assays have proven to be invaluable tools in evaluating the putative effects of the genetic manipulation of C. neoformans strains on the virulence composite of the yeast. In addition, the assay is used to assess the efficacy of various immunotherapeutic agents (i.e., antibodies and cytokines) to enhance this cell-based antifungal activity. The purpose of this chapter is to provide a brief overview on host immunity to C. neoformans infection and, in addition, describe a protocol for performing macrophage phagocytosis and killing assays with C. neoformans and its mutants." @default.
- W1427182169 created "2016-06-24" @default.
- W1427182169 creator A5028777325 @default.
- W1427182169 creator A5068233995 @default.
- W1427182169 date "2005-05-11" @default.
- W1427182169 modified "2023-09-26" @default.
- W1427182169 title "Immunology of Infection Caused by <I>Cryptococcus neoformans</I>" @default.
- W1427182169 cites W2054868502 @default.
- W1427182169 cites W2113796945 @default.
- W1427182169 cites W2115398724 @default.
- W1427182169 cites W2131968022 @default.
- W1427182169 cites W2147038307 @default.
- W1427182169 cites W2158111073 @default.
- W1427182169 cites W2332714587 @default.
- W1427182169 doi "https://doi.org/10.1385/1-59259-943-5:193" @default.
- W1427182169 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15888944" @default.
- W1427182169 hasPublicationYear "2005" @default.
- W1427182169 type Work @default.
- W1427182169 sameAs 1427182169 @default.
- W1427182169 citedByCount "11" @default.
- W1427182169 countsByYear W14271821692012 @default.
- W1427182169 countsByYear W14271821692014 @default.
- W1427182169 countsByYear W14271821692016 @default.
- W1427182169 countsByYear W14271821692017 @default.
- W1427182169 countsByYear W14271821692020 @default.
- W1427182169 countsByYear W14271821692021 @default.
- W1427182169 countsByYear W14271821692022 @default.
- W1427182169 crossrefType "book-chapter" @default.
- W1427182169 hasAuthorship W1427182169A5028777325 @default.
- W1427182169 hasAuthorship W1427182169A5068233995 @default.
- W1427182169 hasConcept C104317684 @default.
- W1427182169 hasConcept C159047783 @default.
- W1427182169 hasConcept C160448771 @default.
- W1427182169 hasConcept C203014093 @default.
- W1427182169 hasConcept C2776460866 @default.
- W1427182169 hasConcept C2777893358 @default.
- W1427182169 hasConcept C2778952914 @default.
- W1427182169 hasConcept C2779341262 @default.
- W1427182169 hasConcept C2779413141 @default.
- W1427182169 hasConcept C54355233 @default.
- W1427182169 hasConcept C60987743 @default.
- W1427182169 hasConcept C86803240 @default.
- W1427182169 hasConcept C8891405 @default.
- W1427182169 hasConcept C89423630 @default.
- W1427182169 hasConceptScore W1427182169C104317684 @default.
- W1427182169 hasConceptScore W1427182169C159047783 @default.
- W1427182169 hasConceptScore W1427182169C160448771 @default.
- W1427182169 hasConceptScore W1427182169C203014093 @default.
- W1427182169 hasConceptScore W1427182169C2776460866 @default.
- W1427182169 hasConceptScore W1427182169C2777893358 @default.
- W1427182169 hasConceptScore W1427182169C2778952914 @default.
- W1427182169 hasConceptScore W1427182169C2779341262 @default.
- W1427182169 hasConceptScore W1427182169C2779413141 @default.
- W1427182169 hasConceptScore W1427182169C54355233 @default.
- W1427182169 hasConceptScore W1427182169C60987743 @default.
- W1427182169 hasConceptScore W1427182169C86803240 @default.
- W1427182169 hasConceptScore W1427182169C8891405 @default.
- W1427182169 hasConceptScore W1427182169C89423630 @default.
- W1427182169 hasLocation W14271821691 @default.
- W1427182169 hasLocation W14271821692 @default.
- W1427182169 hasOpenAccess W1427182169 @default.
- W1427182169 hasPrimaryLocation W14271821691 @default.
- W1427182169 hasRelatedWork W1817460788 @default.
- W1427182169 hasRelatedWork W1959967360 @default.
- W1427182169 hasRelatedWork W2118129764 @default.
- W1427182169 hasRelatedWork W2133094979 @default.
- W1427182169 hasRelatedWork W2137300425 @default.
- W1427182169 hasRelatedWork W2313503697 @default.
- W1427182169 hasRelatedWork W2944870338 @default.
- W1427182169 hasRelatedWork W4226117608 @default.
- W1427182169 hasRelatedWork W4232433239 @default.
- W1427182169 hasRelatedWork W2185437808 @default.
- W1427182169 isParatext "false" @default.
- W1427182169 isRetracted "false" @default.
- W1427182169 magId "1427182169" @default.
- W1427182169 workType "book-chapter" @default.