Matches in SemOpenAlex for { <https://semopenalex.org/work/W1427199114> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1427199114 abstract "Eukaryotic cells need to be in constant communication with their environment in order to perform most of their functions, such as the transmission of neuronal, metabolic, and proliferative signals and the uptake of nutrients or to protect the organism from microbial invasion, to name only a few. Macropinocytosis involves remodeling of the actin cytoskeleton, a process regulated by the small GTPases Ras, Rac, and Cdc42, and leads to massive membrane internalization. Phagocytosis requires important actin rearrangements and pseudopod extension under the control of Rho GTPases. Several pathways have been proposed to mediate membrane traffic between endosomes and the biosynthetic pathway. In particular, several lines of evidence support the view that direct transport routes mediate anterograde and retrograde transport between early endosomes and the trans-Golgi network (TGN). PI3K activity and, hence, PI(3)P are required for autophagy in yeast, where Vps34 has been shown to coimmunoprecipitate with proteins required for autophagy. Early endosomes are important sorting stations along the endocytic pathway. After receptor-ligand uncoupling at the mildly acidic pH (pH 6.2), housekeeping receptors are transported along the recycling route, whereas ligands follow the degradation pathway together with downregulated receptors and fluid phase markers. Phosphorylation of the inositol ring of phosphatidylinositol in the 3, 4, and 5 positions generates seven different phosphoinositides at the cytosolic face of cellular membranes. During the past few years, phosphoinositides have emerged as regulators of membrane traffic by regulating the localization and/or activity of effector proteins." @default.
- W1427199114 created "2016-06-24" @default.
- W1427199114 creator A5033432789 @default.
- W1427199114 creator A5040728880 @default.
- W1427199114 creator A5081295223 @default.
- W1427199114 date "2014-04-30" @default.
- W1427199114 modified "2023-09-27" @default.
- W1427199114 title "Membrane Traffic in the Endocytic Pathway of Eukaryotic Cells" @default.
- W1427199114 cites W1509530066 @default.
- W1427199114 cites W1510287295 @default.
- W1427199114 cites W1520187505 @default.
- W1427199114 cites W1595083713 @default.
- W1427199114 cites W1843137073 @default.
- W1427199114 cites W1963573377 @default.
- W1427199114 cites W1965700082 @default.
- W1427199114 cites W1975126814 @default.
- W1427199114 cites W1977253956 @default.
- W1427199114 cites W1978281474 @default.
- W1427199114 cites W1996120942 @default.
- W1427199114 cites W2014263971 @default.
- W1427199114 cites W2015752928 @default.
- W1427199114 cites W2029732834 @default.
- W1427199114 cites W2041352227 @default.
- W1427199114 cites W2041798988 @default.
- W1427199114 cites W2045279426 @default.
- W1427199114 cites W2054474302 @default.
- W1427199114 cites W2067216245 @default.
- W1427199114 cites W2076864491 @default.
- W1427199114 cites W2086358590 @default.
- W1427199114 cites W2096791952 @default.
- W1427199114 cites W2117352422 @default.
- W1427199114 cites W2119260049 @default.
- W1427199114 cites W2131803903 @default.
- W1427199114 cites W2133987610 @default.
- W1427199114 cites W2135859072 @default.
- W1427199114 cites W2145333947 @default.
- W1427199114 cites W2792139654 @default.
- W1427199114 cites W4211044652 @default.
- W1427199114 doi "https://doi.org/10.1128/9781555817633.ch9" @default.
- W1427199114 hasPublicationYear "2014" @default.
- W1427199114 type Work @default.
- W1427199114 sameAs 1427199114 @default.
- W1427199114 citedByCount "0" @default.
- W1427199114 crossrefType "book-chapter" @default.
- W1427199114 hasAuthorship W1427199114A5033432789 @default.
- W1427199114 hasAuthorship W1427199114A5040728880 @default.
- W1427199114 hasAuthorship W1427199114A5081295223 @default.
- W1427199114 hasConcept C102747710 @default.
- W1427199114 hasConcept C142669718 @default.
- W1427199114 hasConcept C1491633281 @default.
- W1427199114 hasConcept C170493617 @default.
- W1427199114 hasConcept C207332259 @default.
- W1427199114 hasConcept C2780040266 @default.
- W1427199114 hasConcept C28005876 @default.
- W1427199114 hasConcept C2993400109 @default.
- W1427199114 hasConcept C55493867 @default.
- W1427199114 hasConcept C79747257 @default.
- W1427199114 hasConcept C79879829 @default.
- W1427199114 hasConcept C86803240 @default.
- W1427199114 hasConcept C95444343 @default.
- W1427199114 hasConceptScore W1427199114C102747710 @default.
- W1427199114 hasConceptScore W1427199114C142669718 @default.
- W1427199114 hasConceptScore W1427199114C1491633281 @default.
- W1427199114 hasConceptScore W1427199114C170493617 @default.
- W1427199114 hasConceptScore W1427199114C207332259 @default.
- W1427199114 hasConceptScore W1427199114C2780040266 @default.
- W1427199114 hasConceptScore W1427199114C28005876 @default.
- W1427199114 hasConceptScore W1427199114C2993400109 @default.
- W1427199114 hasConceptScore W1427199114C55493867 @default.
- W1427199114 hasConceptScore W1427199114C79747257 @default.
- W1427199114 hasConceptScore W1427199114C79879829 @default.
- W1427199114 hasConceptScore W1427199114C86803240 @default.
- W1427199114 hasConceptScore W1427199114C95444343 @default.
- W1427199114 hasLocation W14271991141 @default.
- W1427199114 hasOpenAccess W1427199114 @default.
- W1427199114 hasPrimaryLocation W14271991141 @default.
- W1427199114 hasRelatedWork W13917541 @default.
- W1427199114 hasRelatedWork W1541002705 @default.
- W1427199114 hasRelatedWork W1597663953 @default.
- W1427199114 hasRelatedWork W1987808051 @default.
- W1427199114 hasRelatedWork W2014899206 @default.
- W1427199114 hasRelatedWork W2019800572 @default.
- W1427199114 hasRelatedWork W2056442594 @default.
- W1427199114 hasRelatedWork W2058921751 @default.
- W1427199114 hasRelatedWork W2064445458 @default.
- W1427199114 hasRelatedWork W2068322045 @default.
- W1427199114 hasRelatedWork W2086811440 @default.
- W1427199114 hasRelatedWork W2088214513 @default.
- W1427199114 hasRelatedWork W2115247117 @default.
- W1427199114 hasRelatedWork W2146599453 @default.
- W1427199114 hasRelatedWork W2165562009 @default.
- W1427199114 hasRelatedWork W2188523333 @default.
- W1427199114 hasRelatedWork W3083799050 @default.
- W1427199114 hasRelatedWork W3130625796 @default.
- W1427199114 hasRelatedWork W5985948 @default.
- W1427199114 hasRelatedWork W2612154479 @default.
- W1427199114 isParatext "false" @default.
- W1427199114 isRetracted "false" @default.
- W1427199114 magId "1427199114" @default.
- W1427199114 workType "book-chapter" @default.