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- W142736904 abstract "Noncoding regulatory genomic elements are central for cellular function, differentiation, and disease, but remain poorly characterized. FAIRE (formaldehyde-assisted isolation of regulatory elements) has emerged as a simple method to identify and analyze active regulatory sequences based on their decreased nucleosomal content. More recently FAIRE was combined with high-throughput sequencing (FAIRE-seq) to locate tissue-specific regulatory elements at a genome scale in purified human pancreatic islets. Here we describe the implementation of the FAIRE method in human pancreatic islet cells." @default.
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- W142736904 date "2011-01-01" @default.
- W142736904 modified "2023-10-06" @default.
- W142736904 title "Mapping Open Chromatin with Formaldehyde-Assisted Isolation of Regulatory Elements" @default.
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- W142736904 doi "https://doi.org/10.1007/978-1-61779-316-5_21" @default.
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