Matches in SemOpenAlex for { <https://semopenalex.org/work/W142776677> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W142776677 endingPage "566" @default.
- W142776677 startingPage "549" @default.
- W142776677 abstract "AbstractThe attenuation of Plasmodium parasites by either radiation or targeted gene deletion can result in viable sporozoites that invade the liver and subsequently arrest. The death of the growth-arrested liver stage parasite and the ensuing recognition by the immune system of parasite antigens promotes protective immunity in immunized mice and humans. The methods described below will enable researchers to determine the efficacy of radiation-attenuated and genetically attenuated rodent malaria sporozoite immunizations against infectious sporozoite challenge, and study protective immunity in immunized mice. In addition, by determining the time of arrest of genetically attenuated parasite liver stages and the mechanisms of clearance, researchers will be able to correlate biological features of the growth-arrested parasites with their ability to promote protective immunity.Key wordsGenetically attenuated parasiteRadiation-attenuated sporozoiteLiver stageProtective immunityCross-stage immunityHeterologous challenge" @default.
- W142776677 created "2016-06-24" @default.
- W142776677 creator A5014639053 @default.
- W142776677 creator A5069042958 @default.
- W142776677 date "2012-01-01" @default.
- W142776677 modified "2023-09-27" @default.
- W142776677 title "Vaccination Using Radiation- or Genetically Attenuated Live Sporozoites" @default.
- W142776677 cites W100984399 @default.
- W142776677 cites W170900791 @default.
- W142776677 cites W1980373415 @default.
- W142776677 cites W2019809965 @default.
- W142776677 cites W2024411676 @default.
- W142776677 cites W2025326880 @default.
- W142776677 cites W2029128803 @default.
- W142776677 cites W2031312154 @default.
- W142776677 cites W2039481952 @default.
- W142776677 cites W2060564531 @default.
- W142776677 cites W2062137938 @default.
- W142776677 cites W2064656497 @default.
- W142776677 cites W2064987052 @default.
- W142776677 cites W2066593591 @default.
- W142776677 cites W2070136956 @default.
- W142776677 cites W2072269419 @default.
- W142776677 cites W2097370940 @default.
- W142776677 cites W2113206880 @default.
- W142776677 cites W2131277865 @default.
- W142776677 cites W2137022726 @default.
- W142776677 cites W2138623091 @default.
- W142776677 cites W2144296388 @default.
- W142776677 cites W2162355257 @default.
- W142776677 doi "https://doi.org/10.1007/978-1-62703-026-7_38" @default.
- W142776677 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22990804" @default.
- W142776677 hasPublicationYear "2012" @default.
- W142776677 type Work @default.
- W142776677 sameAs 142776677 @default.
- W142776677 citedByCount "14" @default.
- W142776677 countsByYear W1427766772013 @default.
- W142776677 countsByYear W1427766772014 @default.
- W142776677 countsByYear W1427766772015 @default.
- W142776677 countsByYear W1427766772017 @default.
- W142776677 countsByYear W1427766772018 @default.
- W142776677 countsByYear W1427766772019 @default.
- W142776677 countsByYear W1427766772020 @default.
- W142776677 crossrefType "book-chapter" @default.
- W142776677 hasAuthorship W142776677A5014639053 @default.
- W142776677 hasAuthorship W142776677A5069042958 @default.
- W142776677 hasConcept C104317684 @default.
- W142776677 hasConcept C136764020 @default.
- W142776677 hasConcept C147483822 @default.
- W142776677 hasConcept C159047783 @default.
- W142776677 hasConcept C203014093 @default.
- W142776677 hasConcept C22070199 @default.
- W142776677 hasConcept C2778048844 @default.
- W142776677 hasConcept C2778675580 @default.
- W142776677 hasConcept C2779341262 @default.
- W142776677 hasConcept C41008148 @default.
- W142776677 hasConcept C51456166 @default.
- W142776677 hasConcept C54355233 @default.
- W142776677 hasConcept C54602769 @default.
- W142776677 hasConcept C60987743 @default.
- W142776677 hasConcept C71928629 @default.
- W142776677 hasConcept C86803240 @default.
- W142776677 hasConcept C8891405 @default.
- W142776677 hasConceptScore W142776677C104317684 @default.
- W142776677 hasConceptScore W142776677C136764020 @default.
- W142776677 hasConceptScore W142776677C147483822 @default.
- W142776677 hasConceptScore W142776677C159047783 @default.
- W142776677 hasConceptScore W142776677C203014093 @default.
- W142776677 hasConceptScore W142776677C22070199 @default.
- W142776677 hasConceptScore W142776677C2778048844 @default.
- W142776677 hasConceptScore W142776677C2778675580 @default.
- W142776677 hasConceptScore W142776677C2779341262 @default.
- W142776677 hasConceptScore W142776677C41008148 @default.
- W142776677 hasConceptScore W142776677C51456166 @default.
- W142776677 hasConceptScore W142776677C54355233 @default.
- W142776677 hasConceptScore W142776677C54602769 @default.
- W142776677 hasConceptScore W142776677C60987743 @default.
- W142776677 hasConceptScore W142776677C71928629 @default.
- W142776677 hasConceptScore W142776677C86803240 @default.
- W142776677 hasConceptScore W142776677C8891405 @default.
- W142776677 hasLocation W1427766771 @default.
- W142776677 hasLocation W1427766772 @default.
- W142776677 hasOpenAccess W142776677 @default.
- W142776677 hasPrimaryLocation W1427766771 @default.
- W142776677 hasRelatedWork W1996463424 @default.
- W142776677 hasRelatedWork W2025767750 @default.
- W142776677 hasRelatedWork W2057145238 @default.
- W142776677 hasRelatedWork W2096696237 @default.
- W142776677 hasRelatedWork W2228521159 @default.
- W142776677 hasRelatedWork W2408061066 @default.
- W142776677 hasRelatedWork W2585098064 @default.
- W142776677 hasRelatedWork W2770242914 @default.
- W142776677 hasRelatedWork W3095528982 @default.
- W142776677 hasRelatedWork W627434472 @default.
- W142776677 isParatext "false" @default.
- W142776677 isRetracted "false" @default.
- W142776677 magId "142776677" @default.
- W142776677 workType "book-chapter" @default.