Matches in SemOpenAlex for { <https://semopenalex.org/work/W1427889567> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1427889567 abstract "Publisher Summary This chapter describes the ouabain binding and Na, K-ATPase in released human red cell ghosts. Resealed ghosts are particularly suitable experimental models as one is able to precisely control the concentration of desired ligands on both sides of the membrane. The study of the interaction of cardiac glycosides with Na, K-ATPase has proved to be an indispensable tool in defining and characterizing numerous properties of the Na, K-ATPase transport complex. Resealed ghosts were prepared by a modification of the method of Bodemann and Passow to contain a high intracellular sodium concentration and various concentrations of Na/K pump ligands. [ 3 H]Ouabain binding assays were performed in a high sodium medium with the concentration of labeled cardiac glycoside ranging from 10 –7 to 10 –8 M . By exposing resealed ghosts to [ 3 H]ouabain for various time periods, preparing hypotonically lysed membranes from these treated ghosts, and assaying the fractional inhibition of the Na, K-ATPase activity, the relationship between the number of ouabain molecules bound per ghost and the fractional inhibition of Na, K-ATPase was obtained. It was found that one molecule of [ 3 H]ouabain was sufficient to inhibit one Na, K-ATPase complex." @default.
- W1427889567 created "2016-06-24" @default.
- W1427889567 creator A5063570977 @default.
- W1427889567 creator A5073658267 @default.
- W1427889567 date "1983-01-01" @default.
- W1427889567 modified "2023-09-23" @default.
- W1427889567 title "Ouabain Binding and Na,K-ATPase in Released Human Red Cell Ghosts" @default.
- W1427889567 cites W1595850806 @default.
- W1427889567 cites W1876365052 @default.
- W1427889567 cites W1981139209 @default.
- W1427889567 cites W2004963309 @default.
- W1427889567 cites W2006990177 @default.
- W1427889567 cites W2009576459 @default.
- W1427889567 cites W2055652819 @default.
- W1427889567 cites W2064779468 @default.
- W1427889567 cites W2111717586 @default.
- W1427889567 cites W2154689939 @default.
- W1427889567 cites W83654277 @default.
- W1427889567 doi "https://doi.org/10.1016/s0070-2161(08)60575-4" @default.
- W1427889567 hasPublicationYear "1983" @default.
- W1427889567 type Work @default.
- W1427889567 sameAs 1427889567 @default.
- W1427889567 citedByCount "0" @default.
- W1427889567 crossrefType "book-chapter" @default.
- W1427889567 hasAuthorship W1427889567A5063570977 @default.
- W1427889567 hasAuthorship W1427889567A5073658267 @default.
- W1427889567 hasConcept C12554922 @default.
- W1427889567 hasConcept C178790620 @default.
- W1427889567 hasConcept C181199279 @default.
- W1427889567 hasConcept C185592680 @default.
- W1427889567 hasConcept C194671627 @default.
- W1427889567 hasConcept C23265538 @default.
- W1427889567 hasConcept C2779133857 @default.
- W1427889567 hasConcept C2780557390 @default.
- W1427889567 hasConcept C41625074 @default.
- W1427889567 hasConcept C537181965 @default.
- W1427889567 hasConcept C55493867 @default.
- W1427889567 hasConcept C57409179 @default.
- W1427889567 hasConcept C71240020 @default.
- W1427889567 hasConcept C79879829 @default.
- W1427889567 hasConcept C86803240 @default.
- W1427889567 hasConceptScore W1427889567C12554922 @default.
- W1427889567 hasConceptScore W1427889567C178790620 @default.
- W1427889567 hasConceptScore W1427889567C181199279 @default.
- W1427889567 hasConceptScore W1427889567C185592680 @default.
- W1427889567 hasConceptScore W1427889567C194671627 @default.
- W1427889567 hasConceptScore W1427889567C23265538 @default.
- W1427889567 hasConceptScore W1427889567C2779133857 @default.
- W1427889567 hasConceptScore W1427889567C2780557390 @default.
- W1427889567 hasConceptScore W1427889567C41625074 @default.
- W1427889567 hasConceptScore W1427889567C537181965 @default.
- W1427889567 hasConceptScore W1427889567C55493867 @default.
- W1427889567 hasConceptScore W1427889567C57409179 @default.
- W1427889567 hasConceptScore W1427889567C71240020 @default.
- W1427889567 hasConceptScore W1427889567C79879829 @default.
- W1427889567 hasConceptScore W1427889567C86803240 @default.
- W1427889567 hasLocation W14278895671 @default.
- W1427889567 hasOpenAccess W1427889567 @default.
- W1427889567 hasPrimaryLocation W14278895671 @default.
- W1427889567 hasRelatedWork W117228613 @default.
- W1427889567 hasRelatedWork W1544129512 @default.
- W1427889567 hasRelatedWork W1635251580 @default.
- W1427889567 hasRelatedWork W1926823425 @default.
- W1427889567 hasRelatedWork W1973889930 @default.
- W1427889567 hasRelatedWork W1980862628 @default.
- W1427889567 hasRelatedWork W2008998360 @default.
- W1427889567 hasRelatedWork W2017023148 @default.
- W1427889567 hasRelatedWork W2021904345 @default.
- W1427889567 hasRelatedWork W2050286267 @default.
- W1427889567 hasRelatedWork W2059570349 @default.
- W1427889567 hasRelatedWork W2082936049 @default.
- W1427889567 hasRelatedWork W2321343015 @default.
- W1427889567 hasRelatedWork W2338705945 @default.
- W1427889567 hasRelatedWork W2339270090 @default.
- W1427889567 hasRelatedWork W2411348693 @default.
- W1427889567 hasRelatedWork W2411680334 @default.
- W1427889567 hasRelatedWork W2412221935 @default.
- W1427889567 hasRelatedWork W2423345061 @default.
- W1427889567 hasRelatedWork W2461433575 @default.
- W1427889567 isParatext "false" @default.
- W1427889567 isRetracted "false" @default.
- W1427889567 magId "1427889567" @default.
- W1427889567 workType "book-chapter" @default.