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- W1429595009 abstract "The aim of this study was to compare cortisol concentrations in plasma (PCC) and milk (MCC) following administration of exogenous ACTH 1-24 or activation of the hypothalamo-pituitary-adrenal axis by a stressor (transport) in cows. Fifteen cows in midlactation were assigned to treatments with ACTH 1-24 (0.05 mg Synacthen™ iv at 1300h), transport (trucking for two 45 min periods from 1300h) or control (sampling only) in a 3x3 Latin square design. Blood samples were collected hourly from 1300-1500h and a composite milk sample was obtained at routine milking at 1515h. There was a 6-fold elevation in PCC by 60 min following both ACTH treatment and transportation. At 120 min, PCC was twofold higher in ACTH treated cows but remained at levels similar to those at 60 min in the transported animals, indicating that the adrenocortical response had been maintained during transport. Mean MCC was 12-fold greater after the transport treatment and a factor of 2 higher after ACTH treatment, compared to the control treatment (P<0.01). Values of MCC and PCC at the 120 min sampling wer e highly correlated (r = 0.80; P<0.001). This suggested that MCC may be a useful indicator of adrenocortical response to stressor s, provided samples are obtained during the period of elevated PCC." @default.
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- W1429595009 date "1996-01-01" @default.
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- W1429595009 title "Milk cortisol concentrations as an indicator of stress in lactating dairy cows" @default.
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