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- W1431989102 abstract "Objective:To study the mechanisms that acupuncture therapy of in treating postmenopausal osteoporosis(PMO).Methods:60female SD rats aged 6 months were resected bilateral ovaries and feeded for 90 days in order to make the model of experimental osteoporosis.Then,they were divided into 5 groups such as control group,regular acupoints treated group,Yitong group,Shuanggu group,with 12 rats each group,and the control group without any treatment;Pishu(BL 20),Weishu(BL 21),Shenshu(BL 23),Qihaishu(BL 24) was selected for the regular acupoints treated group;Guanyuan(RN 4),Zusanli(ST 36) for the Shuanggu group;and Shenshu(BL 23),Geshu(BL 17),Dazhu(BL 11) for the Yitong group;Guanyuan(RN 4),Zusanli(ST 36),Shenshu(BL 23),Geshu(BL 17),Dazhu(BL 11)for the group.Electroacupuncture therapy was given once a day,15 minutes each time,the needles were retained for 10 minutes.Then these rats rested for 1 day after consecutive therapy for 6 days.The therapy lasted for 12 weeks.RT-PCR was used to examine the expression level of interleukin-6(IL-6)mRNA in bone tissue.Results:Compared with control group,the expression level of IL-6mRNA in all acupuncture therapy groups decreased(P0.05),and it decreased significantly in group(P0.01);The index was lower in group than that in regular acupoints treated group and Yitong group(P0.05);The index didn’t differ significantly among regular acupoints treated group and Yitong group(P0.05).Conclusion:Acupuncture can reduce the expression level of IL-6mRNA in osteoporosis model rats without ovaries and acupuncture therapy is superior to other regular acupuncture therapy." @default.
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- W1431989102 date "2009-01-01" @default.
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- W1431989102 title "Effect of Shuanggu Yitong acupuncture therapy on interleukin-6 of experimental rats with postmenopausal osteoporosis." @default.
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