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- W143397309 abstract "Adjuvant imatinib prolongs recurrence-free survival and probably overall survival of patients who have undergone surgery for gastrointestinal stromal tumor (GIST). Estimation of the risk of recurrence with a prognostication tool and tumor mutation analysis is essential before imatinib initiation, because approximately 60% of patients with GIST with operable tumor are cured by surgery alone and some mutated tyrosine kinases are insensitive to imatinib. Adjuvant imatinib is usually administered for 3 years at the dose of 400 mg once daily. Early detection of tumors that recur despite adjuvant therapy with longitudinal imaging of the abdomen is likely beneficial." @default.
- W143397309 created "2016-06-24" @default.
- W143397309 creator A5090618504 @default.
- W143397309 date "2013-10-01" @default.
- W143397309 modified "2023-10-18" @default.
- W143397309 title "Gastrointestinal Stromal Tumors" @default.
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- W143397309 doi "https://doi.org/10.1016/j.hoc.2013.07.004" @default.
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