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- W1434408054 abstract "The chapter describes the Plasmodium rDNA unit. The chapter discusses briefly a feature of the rDNA units of other eukaryotic organisms and then compares and contrasts this with what has been found about the Plasmodium rDNA unit. There are three main areas of interest: (1) the number of ribosomal genes in a haploid genome, (2) the structural variations among individual rDNA units, and (3) the arrangement of these genes with regard to each other. The most striking feature of eukaryotic rDNA units on an evolutionary scale is their similarity. In contrast, perhaps the most interesting features of the rDNA units of the Plasmodium species, and the subject of this review, are the sharp digressions made from what was thought to be standard features of the eukaryotic ribosomal gene. The chapter illustrates a generalized life cycle of mammalian malarias, discussing only the Plasmodium berghei life cycle. The exoerythrocytic forms of the parasite compose the first developmental stage in the mammalian host. This stage initiates with inoculation of sporozoites into the bloodstream and invasion of the liver. The parasites replicate asexually in the liver and are released as exoerythrocytic merozoites into the bloodstream. The organism goes through at least 11 distinct stages in its life cycle, both haploid and diploid. Protein synthesis varies in rate and occurs at different temperatures throughout the cycle." @default.
- W1434408054 created "2016-06-24" @default.
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- W1434408054 date "1986-01-01" @default.
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- W1434408054 title "The Ribosomal Genes of Plasmodium" @default.
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- W1434408054 doi "https://doi.org/10.1016/s0074-7696(08)61429-1" @default.
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