Matches in SemOpenAlex for { <https://semopenalex.org/work/W1436717818> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1436717818 abstract "This chapter focuses on the membrane transport proteins that are the members of the cystic fibrosis transmembrane conductance regulator (CFTR) family. Transporters of this family act as cAMP-dependent chloride channels. Members of this family have only been found in vertebrates. The chapter discusses the nomenclature, biological sources, substrates, known disease associations (cystic fibrosis), phylogenetic trees, topology plot, physical and genetic characteristics, conserved motifs, multiple amino acid sequence alignments, and database accession numbers for members of the CFTR family. Statistical analysis of multiple amino acid sequence comparisons places the cystic fibrosis transmembrane conductance regulator family in the multidrug resistance subdivision of the ATP binding cassette (ABC) superfamily. Transporters of the CFTR family consist of a single polypeptide chain made up of five domains. Many residues, including several long sequence motifs, are well conserved within the cystic fibrosis transmembrane conductance regulator family, including motifs unique to the family, signature motifs of the ABC superfamily, and motifs necessary for function by the criterion of site directed mutagenesis." @default.
- W1436717818 created "2016-06-24" @default.
- W1436717818 creator A5084149189 @default.
- W1436717818 creator A5085401753 @default.
- W1436717818 date "1998-01-01" @default.
- W1436717818 modified "2023-09-27" @default.
- W1436717818 title "Cystic fibrosis transmembrane conductance regulator family" @default.
- W1436717818 cites W1786021994 @default.
- W1436717818 cites W1796913431 @default.
- W1436717818 cites W2010691166 @default.
- W1436717818 cites W2039599894 @default.
- W1436717818 cites W2162097287 @default.
- W1436717818 doi "https://doi.org/10.1016/b978-012303965-1/50012-3" @default.
- W1436717818 hasPublicationYear "1998" @default.
- W1436717818 type Work @default.
- W1436717818 sameAs 1436717818 @default.
- W1436717818 citedByCount "0" @default.
- W1436717818 crossrefType "book-chapter" @default.
- W1436717818 hasAuthorship W1436717818A5084149189 @default.
- W1436717818 hasAuthorship W1436717818A5085401753 @default.
- W1436717818 hasConcept C104317684 @default.
- W1436717818 hasConcept C117745874 @default.
- W1436717818 hasConcept C118892022 @default.
- W1436717818 hasConcept C145822097 @default.
- W1436717818 hasConcept C167625842 @default.
- W1436717818 hasConcept C170493617 @default.
- W1436717818 hasConcept C171897839 @default.
- W1436717818 hasConcept C24530287 @default.
- W1436717818 hasConcept C2776938444 @default.
- W1436717818 hasConcept C2778428886 @default.
- W1436717818 hasConcept C45484198 @default.
- W1436717818 hasConcept C515207424 @default.
- W1436717818 hasConcept C534586 @default.
- W1436717818 hasConcept C54355233 @default.
- W1436717818 hasConcept C55493867 @default.
- W1436717818 hasConcept C6929976 @default.
- W1436717818 hasConcept C86803240 @default.
- W1436717818 hasConceptScore W1436717818C104317684 @default.
- W1436717818 hasConceptScore W1436717818C117745874 @default.
- W1436717818 hasConceptScore W1436717818C118892022 @default.
- W1436717818 hasConceptScore W1436717818C145822097 @default.
- W1436717818 hasConceptScore W1436717818C167625842 @default.
- W1436717818 hasConceptScore W1436717818C170493617 @default.
- W1436717818 hasConceptScore W1436717818C171897839 @default.
- W1436717818 hasConceptScore W1436717818C24530287 @default.
- W1436717818 hasConceptScore W1436717818C2776938444 @default.
- W1436717818 hasConceptScore W1436717818C2778428886 @default.
- W1436717818 hasConceptScore W1436717818C45484198 @default.
- W1436717818 hasConceptScore W1436717818C515207424 @default.
- W1436717818 hasConceptScore W1436717818C534586 @default.
- W1436717818 hasConceptScore W1436717818C54355233 @default.
- W1436717818 hasConceptScore W1436717818C55493867 @default.
- W1436717818 hasConceptScore W1436717818C6929976 @default.
- W1436717818 hasConceptScore W1436717818C86803240 @default.
- W1436717818 hasLocation W14367178181 @default.
- W1436717818 hasOpenAccess W1436717818 @default.
- W1436717818 hasPrimaryLocation W14367178181 @default.
- W1436717818 hasRelatedWork W1126870675 @default.
- W1436717818 hasRelatedWork W1436919086 @default.
- W1436717818 hasRelatedWork W1472096384 @default.
- W1436717818 hasRelatedWork W1911934392 @default.
- W1436717818 hasRelatedWork W1998042582 @default.
- W1436717818 hasRelatedWork W2014149558 @default.
- W1436717818 hasRelatedWork W2039441002 @default.
- W1436717818 hasRelatedWork W2068127763 @default.
- W1436717818 hasRelatedWork W2074574014 @default.
- W1436717818 hasRelatedWork W2093573808 @default.
- W1436717818 hasRelatedWork W2104136593 @default.
- W1436717818 hasRelatedWork W2126968375 @default.
- W1436717818 hasRelatedWork W2138376566 @default.
- W1436717818 hasRelatedWork W2150538509 @default.
- W1436717818 hasRelatedWork W2214680690 @default.
- W1436717818 hasRelatedWork W2268222194 @default.
- W1436717818 hasRelatedWork W2775737957 @default.
- W1436717818 hasRelatedWork W3017078513 @default.
- W1436717818 hasRelatedWork W3100479405 @default.
- W1436717818 hasRelatedWork W40047580 @default.
- W1436717818 isParatext "false" @default.
- W1436717818 isRetracted "false" @default.
- W1436717818 magId "1436717818" @default.
- W1436717818 workType "book-chapter" @default.