Matches in SemOpenAlex for { <https://semopenalex.org/work/W143721070> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W143721070 endingPage "122" @default.
- W143721070 startingPage "117" @default.
- W143721070 abstract "Clustering of EST data is a method for the non-redundant representation of an organisms transcriptome. During clustering of large amounts of EST data, usually some large clusters (>500 sequences) are created. Those can lead to iterative contig builds, consumation of lots of computing time and improbable exon alignments, which is unfavourable. In addition, these clusters sometimes contain transcripts for more than one gene, which is not desired. Such large clusters come into existence due to: (1) large numbers of identical ESTs / high transcript levels; (2) large gene families with highly similar members; (3) false clustering due to a) unremoved vector or rRNA sequences, b) undetected cloning artifacts or c) repetitive elements in UTRs. During pre-processing (filtering and masking) of the sequence raw data, contaminations such as vector or linker sequences as well as bacterial genes are being removed (clipping). In the same process, it is essential to mask repetitive elements in order to avoid wrong clustering due to these sequence stretches. Therefore, determination of UTR repeats (to use in masking) is a method to avoid false clustering. When dealing with organisms where repetitive elements are unknown, it is crucial to extract those sequences from the data prior to clustering. Here we present three in silico approaches to detect UTR repeats using clustered EST data. All three approaches yielded several putative repeats, of which the majority could be proven to be of repetitive nature in the genome. Usage of the predicted repeats enabled us to save computing time while increasing the quality of the clustered data." @default.
- W143721070 created "2016-06-24" @default.
- W143721070 creator A5002023600 @default.
- W143721070 creator A5036441626 @default.
- W143721070 creator A5047370853 @default.
- W143721070 date "2003-01-01" @default.
- W143721070 modified "2023-09-27" @default.
- W143721070 title "In silico prediction of UTR repeats using clustered EST data" @default.
- W143721070 cites W1966585515 @default.
- W143721070 cites W1968782697 @default.
- W143721070 cites W2056817899 @default.
- W143721070 cites W2087064593 @default.
- W143721070 cites W2107775693 @default.
- W143721070 cites W2124281279 @default.
- W143721070 cites W2158714788 @default.
- W143721070 hasPublicationYear "2003" @default.
- W143721070 type Work @default.
- W143721070 sameAs 143721070 @default.
- W143721070 citedByCount "1" @default.
- W143721070 countsByYear W1437210702014 @default.
- W143721070 crossrefType "proceedings-article" @default.
- W143721070 hasAuthorship W143721070A5002023600 @default.
- W143721070 hasAuthorship W143721070A5036441626 @default.
- W143721070 hasAuthorship W143721070A5047370853 @default.
- W143721070 hasConcept C104317684 @default.
- W143721070 hasConcept C141231307 @default.
- W143721070 hasConcept C154945302 @default.
- W143721070 hasConcept C2775905019 @default.
- W143721070 hasConcept C2778112365 @default.
- W143721070 hasConcept C41008148 @default.
- W143721070 hasConcept C54355233 @default.
- W143721070 hasConcept C59582021 @default.
- W143721070 hasConcept C70721500 @default.
- W143721070 hasConcept C73555534 @default.
- W143721070 hasConcept C86803240 @default.
- W143721070 hasConceptScore W143721070C104317684 @default.
- W143721070 hasConceptScore W143721070C141231307 @default.
- W143721070 hasConceptScore W143721070C154945302 @default.
- W143721070 hasConceptScore W143721070C2775905019 @default.
- W143721070 hasConceptScore W143721070C2778112365 @default.
- W143721070 hasConceptScore W143721070C41008148 @default.
- W143721070 hasConceptScore W143721070C54355233 @default.
- W143721070 hasConceptScore W143721070C59582021 @default.
- W143721070 hasConceptScore W143721070C70721500 @default.
- W143721070 hasConceptScore W143721070C73555534 @default.
- W143721070 hasConceptScore W143721070C86803240 @default.
- W143721070 hasLocation W1437210701 @default.
- W143721070 hasOpenAccess W143721070 @default.
- W143721070 hasPrimaryLocation W1437210701 @default.
- W143721070 hasRelatedWork W1520721721 @default.
- W143721070 hasRelatedWork W1528782506 @default.
- W143721070 hasRelatedWork W1973261687 @default.
- W143721070 hasRelatedWork W1980283473 @default.
- W143721070 hasRelatedWork W1984767890 @default.
- W143721070 hasRelatedWork W2030774451 @default.
- W143721070 hasRelatedWork W2041460881 @default.
- W143721070 hasRelatedWork W2055686503 @default.
- W143721070 hasRelatedWork W2109242192 @default.
- W143721070 hasRelatedWork W2109293112 @default.
- W143721070 hasRelatedWork W2119453551 @default.
- W143721070 hasRelatedWork W2130961331 @default.
- W143721070 hasRelatedWork W2138000345 @default.
- W143721070 hasRelatedWork W2150483253 @default.
- W143721070 hasRelatedWork W2161984591 @default.
- W143721070 hasRelatedWork W2254220978 @default.
- W143721070 hasRelatedWork W2742843740 @default.
- W143721070 hasRelatedWork W2790392927 @default.
- W143721070 hasRelatedWork W2897466754 @default.
- W143721070 hasRelatedWork W2962114069 @default.
- W143721070 isParatext "false" @default.
- W143721070 isRetracted "false" @default.
- W143721070 magId "143721070" @default.
- W143721070 workType "article" @default.