FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1445491422> ?p ?o ?g. }

• W1445491422 endingPage "529" @default.
• W1445491422 startingPage "523" @default.
• W1445491422 abstract "We investigated the binding characteristics, content and intracellular distribution of nuclear and cytosolic oestrogen receptors in the uteri of rats bearing a unilateral intrauterine device, fitted 14–18 days earlier, at four phases of a 5-day oestrous cycle. The patterns of changes in wet weight and content of cytosolic and nuclear receptor that normally occur during the oestrous cycle were not altered by the presence of the device. At all stages of the cycle the intra-uterine-device-containing horn had a greater wet weight and a correspondingly higher content of cytosolic receptor than its contralateral control horn, the cellular concentration of cytosolic receptor being apparently maintained. However, the intra-uterine-device-containing horn had significantly lower cellular concentrations (i.e. per mg of DNA) of nuclear receptor, particularly at late dioestrus and pro-oestrus. Thus the treated horn showed a decreased translocation of receptor in response to increases in circulating oestrogens. Both horns contained equivalent amounts of an activating factor implicated in translocation and measured in vitro by binding of cytosol receptor to oligo(dT)-cellulose. The presence of an intra-uterine device neither altered the dissociation constants (Kd) of the nuclear and cytosolic oestrogen-receptor complexes nor the stability of the nuclear receptor complex in vitro. The decreased translocation cannot thus be directly attributed to changes in the physical properties of the receptor. This decrease may be responsible for the anti-fertility effect of the intra-uterine device (which affects only the treated horn of the bicornuate rat uterus), since implantation of the blastocyst requires correct concentrations of nuclear oestrogen receptor." @default.
• W1445491422 created "2016-06-24" @default.
• W1445491422 creator A5030413543 @default.
• W1445491422 creator A5048209900 @default.
• W1445491422 creator A5053395257 @default.
• W1445491422 creator A5083895051 @default.
• W1445491422 date "1978-11-15" @default.
• W1445491422 modified "2023-09-25" @default.
• W1445491422 title "The oestrogen receptor in the rat uterus in relation to intra-uterine devices and the oestrous cycle" @default.
• W1445491422 cites W1515245060 @default.
• W1445491422 cites W165786424 @default.
• W1445491422 cites W1906197854 @default.
• W1445491422 cites W1998050113 @default.
• W1445491422 cites W2006591487 @default.
• W1445491422 cites W2043012745 @default.
• W1445491422 cites W2047880182 @default.
• W1445491422 cites W2058504444 @default.
• W1445491422 cites W2063188265 @default.
• W1445491422 cites W2063557754 @default.
• W1445491422 cites W2074361623 @default.
• W1445491422 cites W2088763531 @default.
• W1445491422 cites W2091988211 @default.
• W1445491422 cites W2215387789 @default.
• W1445491422 cites W2215525181 @default.
• W1445491422 cites W2225965447 @default.
• W1445491422 cites W2261816148 @default.
• W1445491422 cites W2269288167 @default.
• W1445491422 cites W234618493 @default.
• W1445491422 cites W2415371663 @default.
• W1445491422 cites W981333675 @default.
• W1445491422 cites W2427204746 @default.
• W1445491422 doi "https://doi.org/10.1042/bj1760523" @default.
• W1445491422 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1186261" @default.
• W1445491422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/570396" @default.
• W1445491422 hasPublicationYear "1978" @default.
• W1445491422 type Work @default.
• W1445491422 sameAs 1445491422 @default.
• W1445491422 citedByCount "17" @default.
• W1445491422 countsByYear W14454914222012 @default.
• W1445491422 countsByYear W14454914222019 @default.
• W1445491422 crossrefType "journal-article" @default.
• W1445491422 hasAuthorship W1445491422A5030413543 @default.
• W1445491422 hasAuthorship W1445491422A5048209900 @default.
• W1445491422 hasAuthorship W1445491422A5053395257 @default.
• W1445491422 hasAuthorship W1445491422A5083895051 @default.
• W1445491422 hasBestOaLocation W14454914222 @default.
• W1445491422 hasConcept C104317684 @default.
• W1445491422 hasConcept C121608353 @default.
• W1445491422 hasConcept C126322002 @default.
• W1445491422 hasConcept C134018914 @default.
• W1445491422 hasConcept C138626823 @default.
• W1445491422 hasConcept C16685009 @default.
• W1445491422 hasConcept C170493617 @default.
• W1445491422 hasConcept C181199279 @default.
• W1445491422 hasConcept C185592680 @default.
• W1445491422 hasConcept C1998276 @default.
• W1445491422 hasConcept C2778227567 @default.
• W1445491422 hasConcept C2779066055 @default.
• W1445491422 hasConcept C530470458 @default.
• W1445491422 hasConcept C55493867 @default.
• W1445491422 hasConcept C71924100 @default.
• W1445491422 hasConcept C84606932 @default.
• W1445491422 hasConcept C86803240 @default.
• W1445491422 hasConcept C98539663 @default.
• W1445491422 hasConcept C98717036 @default.
• W1445491422 hasConceptScore W1445491422C104317684 @default.
• W1445491422 hasConceptScore W1445491422C121608353 @default.
• W1445491422 hasConceptScore W1445491422C126322002 @default.
• W1445491422 hasConceptScore W1445491422C134018914 @default.
• W1445491422 hasConceptScore W1445491422C138626823 @default.
• W1445491422 hasConceptScore W1445491422C16685009 @default.
• W1445491422 hasConceptScore W1445491422C170493617 @default.
• W1445491422 hasConceptScore W1445491422C181199279 @default.
• W1445491422 hasConceptScore W1445491422C185592680 @default.
• W1445491422 hasConceptScore W1445491422C1998276 @default.
• W1445491422 hasConceptScore W1445491422C2778227567 @default.
• W1445491422 hasConceptScore W1445491422C2779066055 @default.
• W1445491422 hasConceptScore W1445491422C530470458 @default.
• W1445491422 hasConceptScore W1445491422C55493867 @default.
• W1445491422 hasConceptScore W1445491422C71924100 @default.
• W1445491422 hasConceptScore W1445491422C84606932 @default.
• W1445491422 hasConceptScore W1445491422C86803240 @default.
• W1445491422 hasConceptScore W1445491422C98539663 @default.
• W1445491422 hasConceptScore W1445491422C98717036 @default.
• W1445491422 hasIssue "2" @default.
• W1445491422 hasLocation W14454914221 @default.
• W1445491422 hasLocation W14454914222 @default.
• W1445491422 hasLocation W14454914223 @default.
• W1445491422 hasLocation W14454914224 @default.
• W1445491422 hasOpenAccess W1445491422 @default.
• W1445491422 hasPrimaryLocation W14454914221 @default.
• W1445491422 hasRelatedWork W1969419739 @default.
• W1445491422 hasRelatedWork W2000124881 @default.
• W1445491422 hasRelatedWork W2013275608 @default.
• W1445491422 hasRelatedWork W2014570372 @default.
• W1445491422 hasRelatedWork W2036659686 @default.
• W1445491422 hasRelatedWork W2057217014 @default.
• W1445491422 hasRelatedWork W2093476509 @default.

• next