Matches in SemOpenAlex for { <https://semopenalex.org/work/W144584446> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W144584446 endingPage "16" @default.
- W144584446 startingPage "703" @default.
- W144584446 abstract "The histopathological and electron microscopic features of experimental dermatophytosis due to Trichophyton quinckeanum in Balb/c mice have been studied in animals with primary, secondary and chronic infections. Infected animals all showed pathological changes with adherence of microconidia to keratinocytes within 4 h of infection. Other features were the early infiltration of neutrophils, the formation of a mycelial mass (scutulum) in the epidermis, and epidermal oedema. Increased thickness of the epidermis was measured within 3 days of infection, although this was mainly due to oedema. The main differences seen in secondary infections were the paucity of fungal elements, even after 24 h, a sustained increase in epidermal thickness, and the dense dermal infiltrate of mononuclear cells. Chronically infected animals showed similar changes to those at the peak of a primary infection, but in addition there were large numbers of mast cells in the dermis. Cells carrying Ia markers were identified in the epidermis (Langerhans cells) and the dermis (macrophages) in all infections and their distribution did not appear to change. Although recovery from infection has been correlated previously with T lymphocyte mediated responses an increase in the number of cell layers of the epidermis and a dense infiltrate of neutrophils at the zone of infection were both seen within 2 days of infection. It is suggested that neutrophil killing of fungi and increased epidermal proliferation, not dependent on T cell activation, may also be implicated in host defence against dermatophytes." @default.
- W144584446 created "2016-06-24" @default.
- W144584446 creator A5020576176 @default.
- W144584446 creator A5026219527 @default.
- W144584446 creator A5091678214 @default.
- W144584446 date "1988-10-01" @default.
- W144584446 modified "2023-09-27" @default.
- W144584446 title "Experimental dermatophytosis in mice: correlation between light and electron microscopic changes in primary, secondary and chronic infections." @default.
- W144584446 cites W1578318442 @default.
- W144584446 cites W1994624515 @default.
- W144584446 cites W2039544233 @default.
- W144584446 cites W2054203975 @default.
- W144584446 cites W2057690957 @default.
- W144584446 cites W2071047529 @default.
- W144584446 cites W2124946828 @default.
- W144584446 cites W2132505722 @default.
- W144584446 cites W2163570671 @default.
- W144584446 cites W2402053054 @default.
- W144584446 cites W2413036774 @default.
- W144584446 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2013278" @default.
- W144584446 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3196658" @default.
- W144584446 hasPublicationYear "1988" @default.
- W144584446 type Work @default.
- W144584446 sameAs 144584446 @default.
- W144584446 citedByCount "8" @default.
- W144584446 countsByYear W1445844462015 @default.
- W144584446 countsByYear W1445844462016 @default.
- W144584446 countsByYear W1445844462022 @default.
- W144584446 crossrefType "journal-article" @default.
- W144584446 hasAuthorship W144584446A5020576176 @default.
- W144584446 hasAuthorship W144584446A5026219527 @default.
- W144584446 hasAuthorship W144584446A5091678214 @default.
- W144584446 hasConcept C105702510 @default.
- W144584446 hasConcept C121332964 @default.
- W144584446 hasConcept C137061746 @default.
- W144584446 hasConcept C142724271 @default.
- W144584446 hasConcept C153400128 @default.
- W144584446 hasConcept C167464567 @default.
- W144584446 hasConcept C202751555 @default.
- W144584446 hasConcept C203014093 @default.
- W144584446 hasConcept C2776458125 @default.
- W144584446 hasConcept C2777624698 @default.
- W144584446 hasConcept C55493867 @default.
- W144584446 hasConcept C71924100 @default.
- W144584446 hasConcept C86803240 @default.
- W144584446 hasConcept C97355855 @default.
- W144584446 hasConceptScore W144584446C105702510 @default.
- W144584446 hasConceptScore W144584446C121332964 @default.
- W144584446 hasConceptScore W144584446C137061746 @default.
- W144584446 hasConceptScore W144584446C142724271 @default.
- W144584446 hasConceptScore W144584446C153400128 @default.
- W144584446 hasConceptScore W144584446C167464567 @default.
- W144584446 hasConceptScore W144584446C202751555 @default.
- W144584446 hasConceptScore W144584446C203014093 @default.
- W144584446 hasConceptScore W144584446C2776458125 @default.
- W144584446 hasConceptScore W144584446C2777624698 @default.
- W144584446 hasConceptScore W144584446C55493867 @default.
- W144584446 hasConceptScore W144584446C71924100 @default.
- W144584446 hasConceptScore W144584446C86803240 @default.
- W144584446 hasConceptScore W144584446C97355855 @default.
- W144584446 hasIssue "5" @default.
- W144584446 hasLocation W1445844461 @default.
- W144584446 hasOpenAccess W144584446 @default.
- W144584446 hasPrimaryLocation W1445844461 @default.
- W144584446 hasRelatedWork W144584446 @default.
- W144584446 hasRelatedWork W1976822217 @default.
- W144584446 hasRelatedWork W2026083566 @default.
- W144584446 hasRelatedWork W2039779854 @default.
- W144584446 hasRelatedWork W2077214677 @default.
- W144584446 hasRelatedWork W2407163039 @default.
- W144584446 hasRelatedWork W2411844080 @default.
- W144584446 hasRelatedWork W2416466513 @default.
- W144584446 hasRelatedWork W2992251649 @default.
- W144584446 hasRelatedWork W4288926863 @default.
- W144584446 hasVolume "69" @default.
- W144584446 isParatext "false" @default.
- W144584446 isRetracted "false" @default.
- W144584446 magId "144584446" @default.
- W144584446 workType "article" @default.