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- W1451723869 abstract "This chapter reviews the methods used to study synaptosomal protein phosphorylatio to evaluate the limitations of the procedures and the likelihood of introducing in vitro artefacts. It describes the major synaptosomal phosphoproteins and the effect of depolarization on their labeling with 32Pi. The chapter focuses on phosphoproteins having molecular weights between 40 and 90 kDa because these proteins have been extensively investigated in disrupted synaptic tissue. The chapter describes mechanisms of protein kinase activation and control, which account for the observed phosphorylation of proteins before and after depolarization, and outlines the possible functions of the major synaptosomal phosphoproteins in relation to neurotransmitter release. A number of experimental systems have been used to investigate the role(s) of protein phosphorylation in neurotransmitter release and, out of these, synaptosome preparations constitute an excellent model. These subcellular organelles have the particular advantage of being an in vitro nerve terminal preparation that retains the capacity to release neurotransmitters in a physiologically relevant manner. They are relatively homogeneous compared to neuronal cell cultures containing axons, cell bodies, dendrites and nuclei, and brain slices, which contain nonneuronal cells." @default.
- W1451723869 created "2016-06-24" @default.
- W1451723869 creator A5005523254 @default.
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- W1451723869 date "1986-01-01" @default.
- W1451723869 modified "2023-10-18" @default.
- W1451723869 title "Chapter 22 Depolarization-dependent protein phosphorylation in synaptosomes: mechanisms and significance" @default.
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- W1451723869 cites W1762710702 @default.
- W1451723869 cites W1947163883 @default.
- W1451723869 cites W1965921788 @default.
- W1451723869 cites W1972199495 @default.
- W1451723869 cites W1976645110 @default.
- W1451723869 cites W1977758375 @default.
- W1451723869 cites W1978151819 @default.
- W1451723869 cites W1980643090 @default.
- W1451723869 cites W1982764833 @default.
- W1451723869 cites W1984178221 @default.
- W1451723869 cites W1984233191 @default.
- W1451723869 cites W1984278998 @default.
- W1451723869 cites W1992172937 @default.
- W1451723869 cites W1995384395 @default.
- W1451723869 cites W1996310673 @default.
- W1451723869 cites W1996825405 @default.
- W1451723869 cites W1997326900 @default.
- W1451723869 cites W2000547771 @default.
- W1451723869 cites W2002759605 @default.
- W1451723869 cites W2006366473 @default.
- W1451723869 cites W2008622254 @default.
- W1451723869 cites W2010254256 @default.
- W1451723869 cites W2014727836 @default.
- W1451723869 cites W2014907735 @default.
- W1451723869 cites W2018275786 @default.
- W1451723869 cites W2019325958 @default.
- W1451723869 cites W2020420593 @default.
- W1451723869 cites W2023926350 @default.
- W1451723869 cites W2024994073 @default.
- W1451723869 cites W2025010851 @default.
- W1451723869 cites W2028256752 @default.
- W1451723869 cites W2030012819 @default.
- W1451723869 cites W2032862924 @default.
- W1451723869 cites W2035163189 @default.
- W1451723869 cites W2037741574 @default.
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- W1451723869 cites W2044758569 @default.
- W1451723869 cites W2047520076 @default.
- W1451723869 cites W2050322177 @default.
- W1451723869 cites W2053359523 @default.
- W1451723869 cites W2058326477 @default.
- W1451723869 cites W2061006930 @default.
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- W1451723869 cites W2069581540 @default.
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- W1451723869 doi "https://doi.org/10.1016/s0079-6123(08)61065-1" @default.
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