Matches in SemOpenAlex for { <https://semopenalex.org/work/W145194631> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W145194631 abstract "A specific-pathogen-free (SPF) colony of mice was developed by fostering cesarean-derived CF#1 mice on SPFCFN rats. Fecal cultures showed none of the mice to be positive for Salmonella, or any other organisms considered to be pathogens. There was, however, a hlgh incidence of P. aeruginosa, an organism usually present in a low incidence in conventional CF#1 mice. Because the mice appeared healthy, it was assumed that P. aeruginosa in the intestinal tract was not necessarily detrimental and that the unusual flora was perhaps a phenomenon of SPF development. After production of SPF-CF#1 mice had proceeded for some months, however, marked differences were noted in the response of these mice to radiation. X-ray doses that would kill conventional CF#1 mice in 48 to 72 hr killed the SPF stock in only a few hours. These findings were associated with the high incidence of P. aeruginosa and led to studies of ways to control, or possibly eliminate, this organism. Colistin sulfate in the drinking water significantly reduced the incidence of P. aeruginosa in these mice, as judged by cultures of intestinal contents. The reduced incidence was successfully maintained for a 20week period. Irradiation at the end of this time, in most instances,more » confirmed the bacteriological findings. The percentages of infected control and colistin-treated CF#1 mice were the same before and after 800-r whole- body x irradiation. (BBB)« less" @default.
- W145194631 created "2016-06-24" @default.
- W145194631 creator A5023887711 @default.
- W145194631 creator A5033391828 @default.
- W145194631 date "1963-02-01" @default.
- W145194631 modified "2023-09-26" @default.
- W145194631 title "A STUDY IN THE CONTROL OF PSEUDOMONAS AERUGINOSA IN MICE BY COLISTIN SULFATE" @default.
- W145194631 hasPublicationYear "1963" @default.
- W145194631 type Work @default.
- W145194631 sameAs 145194631 @default.
- W145194631 citedByCount "2" @default.
- W145194631 crossrefType "journal-article" @default.
- W145194631 hasAuthorship W145194631A5023887711 @default.
- W145194631 hasAuthorship W145194631A5033391828 @default.
- W145194631 hasConcept C120665830 @default.
- W145194631 hasConcept C121332964 @default.
- W145194631 hasConcept C2776460866 @default.
- W145194631 hasConcept C2777637488 @default.
- W145194631 hasConcept C2779259085 @default.
- W145194631 hasConcept C42407357 @default.
- W145194631 hasConcept C501593827 @default.
- W145194631 hasConcept C523546767 @default.
- W145194631 hasConcept C54355233 @default.
- W145194631 hasConcept C61511704 @default.
- W145194631 hasConcept C61716771 @default.
- W145194631 hasConcept C86803240 @default.
- W145194631 hasConcept C89423630 @default.
- W145194631 hasConceptScore W145194631C120665830 @default.
- W145194631 hasConceptScore W145194631C121332964 @default.
- W145194631 hasConceptScore W145194631C2776460866 @default.
- W145194631 hasConceptScore W145194631C2777637488 @default.
- W145194631 hasConceptScore W145194631C2779259085 @default.
- W145194631 hasConceptScore W145194631C42407357 @default.
- W145194631 hasConceptScore W145194631C501593827 @default.
- W145194631 hasConceptScore W145194631C523546767 @default.
- W145194631 hasConceptScore W145194631C54355233 @default.
- W145194631 hasConceptScore W145194631C61511704 @default.
- W145194631 hasConceptScore W145194631C61716771 @default.
- W145194631 hasConceptScore W145194631C86803240 @default.
- W145194631 hasConceptScore W145194631C89423630 @default.
- W145194631 hasLocation W1451946311 @default.
- W145194631 hasOpenAccess W145194631 @default.
- W145194631 hasPrimaryLocation W1451946311 @default.
- W145194631 hasRelatedWork W1951873137 @default.
- W145194631 hasRelatedWork W1986520748 @default.
- W145194631 hasRelatedWork W2019147598 @default.
- W145194631 hasRelatedWork W2038481960 @default.
- W145194631 hasRelatedWork W2057016071 @default.
- W145194631 hasRelatedWork W2079782603 @default.
- W145194631 hasRelatedWork W2081517806 @default.
- W145194631 hasRelatedWork W2104645507 @default.
- W145194631 hasRelatedWork W2104977988 @default.
- W145194631 hasRelatedWork W2137990538 @default.
- W145194631 hasRelatedWork W2144961789 @default.
- W145194631 hasRelatedWork W2168250604 @default.
- W145194631 hasRelatedWork W2312756671 @default.
- W145194631 hasRelatedWork W2337423575 @default.
- W145194631 hasRelatedWork W2397661532 @default.
- W145194631 hasRelatedWork W2402625673 @default.
- W145194631 hasRelatedWork W2414939376 @default.
- W145194631 hasRelatedWork W26721958 @default.
- W145194631 hasRelatedWork W2800296836 @default.
- W145194631 hasRelatedWork W83607104 @default.
- W145194631 isParatext "false" @default.
- W145194631 isRetracted "false" @default.
- W145194631 magId "145194631" @default.
- W145194631 workType "article" @default.