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- W145329369 abstract "Role of lipid peroxidation in the pathogenesis of gastrointestinal diseases has been evaluated by measuring the tissue levels of lipid peroxides as thiobarbituric acid-reactive substances in the animal models as well as human. Recently, N ε-(hexanoyl)lysine (HEL) and 4-hydroxy-2-nonenal (HNE) are recognized as reliable and sensitive biomarkers for the early phase and the late phase of lipid peroxidation, respectively. The presence of HNE- and HEL-modified proteins has been demonstrated in in vivo models of several gastrointestinal diseases. In the present review, we introduced HNE-modification of TRPV1 channel in esophageal epithelial cells, HEL-modification of tropomyosin 1 (TMP1) in gastric cancer cells, and HEL-modification of gastrokine 1 in the healing of gastric ulcer." @default.
- W145329369 created "2016-06-24" @default.
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- W145329369 date "2013-12-11" @default.
- W145329369 modified "2023-10-03" @default.
- W145329369 title "Lipid Hydroperoxide-Derived Modification of Proteins in Gastrointestinal Tract" @default.
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- W145329369 doi "https://doi.org/10.1007/978-94-007-7920-4_12" @default.
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