FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1453869219> ?p ?o ?g. }

• W1453869219 endingPage "3537" @default.
• W1453869219 startingPage "3527" @default.
• W1453869219 abstract "The Z-band in vertebrate striated muscle crosslinks actin filaments of opposite polarity from adjoining sarcomeres and transmits tension along myofibrils during muscular contraction. It is also the location of a number of proteins involved in signalling and myofibrillogenesis; mutations in these proteins lead to myopathies. Understanding the high-resolution structure of the Z-band will help us understand its role in muscle contraction and the role of these proteins in the function of muscle. The appearance of the Z-band in transverse-section electron micrographs typically resembles a small-square lattice or a basketweave appearance. In longitudinal sections, the Z-band width varies more with muscle type than species: slow skeletal and cardiac muscles have wider Z-bands than fast skeletal muscles. As the Z-band is periodic, Fourier methods have previously been used for three-dimensional structural analysis. To cope with variations in the periodic structure of the Z-band, we have used subtomogram averaging of tomograms of rat cardiac muscle in which subtomograms are extracted and compared and similar ones are averaged. We show that the Z-band comprises four to six layers of links, presumably α-actinin, linking antiparallel overlapping ends of the actin filaments from the adjoining sarcomeres. The reconstruction shows that the terminal 5–7 nm of the actin filaments within the Z-band is devoid of any α-actinin links and is likely to be the location of capping protein CapZ." @default.
• W1453869219 created "2016-06-24" @default.
• W1453869219 creator A5019076952 @default.
• W1453869219 creator A5036496757 @default.
• W1453869219 creator A5063142765 @default.
• W1453869219 date "2015-11-01" @default.
• W1453869219 modified "2023-09-27" @default.
• W1453869219 title "Three-Dimensional Structure of Vertebrate Muscle Z-Band: The Small-Square Lattice Z-Band in Rat Cardiac Muscle" @default.
• W1453869219 cites W1499880129 @default.
• W1453869219 cites W1520280988 @default.
• W1453869219 cites W1968044246 @default.
• W1453869219 cites W1975227291 @default.
• W1453869219 cites W1977379451 @default.
• W1453869219 cites W1994371103 @default.
• W1453869219 cites W1999370812 @default.
• W1453869219 cites W2003480695 @default.
• W1453869219 cites W2005209296 @default.
• W1453869219 cites W2007120841 @default.
• W1453869219 cites W2021400994 @default.
• W1453869219 cites W2028605946 @default.
• W1453869219 cites W2033028307 @default.
• W1453869219 cites W2041611268 @default.
• W1453869219 cites W2049207651 @default.
• W1453869219 cites W2050292589 @default.
• W1453869219 cites W2066963587 @default.
• W1453869219 cites W2068277549 @default.
• W1453869219 cites W2068643393 @default.
• W1453869219 cites W2075347749 @default.
• W1453869219 cites W2075735274 @default.
• W1453869219 cites W2076143388 @default.
• W1453869219 cites W2076200210 @default.
• W1453869219 cites W2079149769 @default.
• W1453869219 cites W2079161230 @default.
• W1453869219 cites W2083779268 @default.
• W1453869219 cites W2086639577 @default.
• W1453869219 cites W2089155140 @default.
• W1453869219 cites W2091202339 @default.
• W1453869219 cites W2101962726 @default.
• W1453869219 cites W2105257979 @default.
• W1453869219 cites W2105714029 @default.
• W1453869219 cites W2111366557 @default.
• W1453869219 cites W2111392850 @default.
• W1453869219 cites W2114811456 @default.
• W1453869219 cites W2127436402 @default.
• W1453869219 cites W2133900795 @default.
• W1453869219 cites W2139229287 @default.
• W1453869219 cites W2168157247 @default.
• W1453869219 cites W64866819 @default.
• W1453869219 doi "https://doi.org/10.1016/j.jmb.2015.08.018" @default.
• W1453869219 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4641244" @default.
• W1453869219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26362007" @default.
• W1453869219 hasPublicationYear "2015" @default.
• W1453869219 type Work @default.
• W1453869219 sameAs 1453869219 @default.
• W1453869219 citedByCount "24" @default.
• W1453869219 countsByYear W14538692192017 @default.
• W1453869219 countsByYear W14538692192018 @default.
• W1453869219 countsByYear W14538692192019 @default.
• W1453869219 countsByYear W14538692192020 @default.
• W1453869219 countsByYear W14538692192021 @default.
• W1453869219 countsByYear W14538692192022 @default.
• W1453869219 countsByYear W14538692192023 @default.
• W1453869219 crossrefType "journal-article" @default.
• W1453869219 hasAuthorship W1453869219A5019076952 @default.
• W1453869219 hasAuthorship W1453869219A5036496757 @default.
• W1453869219 hasAuthorship W1453869219A5063142765 @default.
• W1453869219 hasBestOaLocation W14538692191 @default.
• W1453869219 hasConcept C105702510 @default.
• W1453869219 hasConcept C120665830 @default.
• W1453869219 hasConcept C121332964 @default.
• W1453869219 hasConcept C12554922 @default.
• W1453869219 hasConcept C125705527 @default.
• W1453869219 hasConcept C133702464 @default.
• W1453869219 hasConcept C142669718 @default.
• W1453869219 hasConcept C1491633281 @default.
• W1453869219 hasConcept C174054327 @default.
• W1453869219 hasConcept C185592680 @default.
• W1453869219 hasConcept C207200792 @default.
• W1453869219 hasConcept C2776050358 @default.
• W1453869219 hasConcept C2778996579 @default.
• W1453869219 hasConcept C2779959927 @default.
• W1453869219 hasConcept C3018767501 @default.
• W1453869219 hasConcept C55493867 @default.
• W1453869219 hasConcept C68731436 @default.
• W1453869219 hasConcept C7301908 @default.
• W1453869219 hasConcept C8010536 @default.
• W1453869219 hasConcept C86803240 @default.
• W1453869219 hasConcept C93877712 @default.
• W1453869219 hasConcept C95444343 @default.
• W1453869219 hasConceptScore W1453869219C105702510 @default.
• W1453869219 hasConceptScore W1453869219C120665830 @default.
• W1453869219 hasConceptScore W1453869219C121332964 @default.
• W1453869219 hasConceptScore W1453869219C12554922 @default.
• W1453869219 hasConceptScore W1453869219C125705527 @default.
• W1453869219 hasConceptScore W1453869219C133702464 @default.
• W1453869219 hasConceptScore W1453869219C142669718 @default.
• W1453869219 hasConceptScore W1453869219C1491633281 @default.
• W1453869219 hasConceptScore W1453869219C174054327 @default.

• next