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- W1453874146 abstract "Now, one of the peculiar characteristics of the savage in his domestic hours, is his wonderful patience of industry. An ancient Hawaiian war-club or spear-paddle, in its full multiplicity and elaboration of carving, is as great a trophy of human perseverance as a Latin lexicon. For, with but a bit of broken sea-shell or a shark's tooth, that miraculous intricacy of wooden network has been achieved; and it has cost steady years of steady application. Neuronal function involves the interaction of electrical and chemical signals that are distributed in time and space. The mechanisms that generate these signals and regulate their interactions are marked by a wide diversity of properties, differing across neuronal cell class, developmental stage, and species (e.g. Chapter 7 in (Johnston and Wu 1995); also see (McCormick 1998)). To be useful in research, a simulation environment must provide a flexible and powerful means for incorporating new biophysical mechanisms in models. It must also help the user remain focused on the model instead of programming. Such a means is provided to NEURON by NMODL, a high level language that was originally implemented for NEURON by Michael Hines and later extended by him and Upinder Bhalla to generate code suitable for linking with GENESIS (Wilson and Bower 1989)." @default.
- W1453874146 created "2016-06-24" @default.
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- W1453874146 date "2006-01-12" @default.
- W1453874146 modified "2023-10-16" @default.
- W1453874146 title "How to expand NEURON's library of mechanisms" @default.
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- W1453874146 doi "https://doi.org/10.1017/cbo9780511541612.010" @default.
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