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- W1454129187 abstract "Compounds having carbostyril (2-quinolones) moiety are associated with interesting biological activities. In the present study, we synthesized Schiff bases of 7-amino-4-methyl carbostyrils and their antibacterial activity wasevaluated by agar diffusion method. The 7-amino-4-methyl carbostyrils were prepared by reacting m-phenylene diamine and β-ketoester by the Conard-Limpach synthesis. Schiff bases of 7-amino-4-methyl carbostyrils (1 to 10) were prepared by reacting 7-amino-4-methyl carbostyril withsubstituted aromatic aldehydes. The final test compounds were purified and characterized by the UV, IR, 1HNMR and Mass Spectral studies. They were evaluated for antibacterial activity. Four test compounds, such as 3, 6, 8 and 9 were active against Bacillus subtilis while Amoxicillin and Gentamycin were used as standards." @default.
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- W1454129187 date "2009-01-01" @default.
- W1454129187 modified "2023-09-24" @default.
- W1454129187 title "Newer carbostyril derivatives for antibacterial activity" @default.
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