FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W145418268> ?p ?o ?g. }

• W145418268 endingPage "191" @default.
• W145418268 startingPage "181" @default.
• W145418268 abstract "Metastasis is a complex process composed of sequential events involving host celltumor cell interactions, which enable tumor cells to disseminate from the primary site to distant locations (1). To successfully establish a secondary metastatic colony, tumor cells must be able to overcome all of the steps in the metastatic cascade, including detachment, intravasation, arrest, extravasation and proliferation. Ample cell-host interactions, such as tumor cell-platelet, tumor cell-endothelial cell and tumor cell-matrix protein interaction, are influenced by positive and negative regulatory factors. Eicosanoids and other bioactive lipids have been shown to be involved in various aspects of neoplasia including cell transformation, proliferation, apoptosis, invasion and metastasis. Platelets and endothelial cells with which tumor cells interaction during hematogenous metastasis are capable of producing a vast array of lipid mediators by either direct or transcellular metabolism of precursors. Platelets and some tumor cells are capable of converting arachidonic acid (AA) through the 12-lipoxygenase (12-LOX) pathway into 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE). A large collection of experimental data suggest that 12(S)-HETE plays a pivotal role in multiple steps of the metastatic cascade encompassing tumor cell-vasculature interaction, tumor cell motility, proteolysis, invasion, and angiogenesis. In this review we summarize the effects of 12(S)-HETE in modulating tumor metastasis." @default.
• W145418268 created "2016-06-24" @default.
• W145418268 creator A5044817021 @default.
• W145418268 creator A5046194281 @default.
• W145418268 date "1999-01-01" @default.
• W145418268 modified "2023-09-27" @default.
• W145418268 title "12(S)-HETE in Cancer Metastasis" @default.
• W145418268 cites W150430194 @default.
• W145418268 cites W1504633391 @default.
• W145418268 cites W1521629024 @default.
• W145418268 cites W1532774873 @default.
• W145418268 cites W1543921112 @default.
• W145418268 cites W1556092333 @default.
• W145418268 cites W1567180128 @default.
• W145418268 cites W1891923627 @default.
• W145418268 cites W1911310945 @default.
• W145418268 cites W1964626290 @default.
• W145418268 cites W1964942556 @default.
• W145418268 cites W1965978680 @default.
• W145418268 cites W1969632293 @default.
• W145418268 cites W1971719930 @default.
• W145418268 cites W1975517899 @default.
• W145418268 cites W1975733077 @default.
• W145418268 cites W1977600524 @default.
• W145418268 cites W1986155420 @default.
• W145418268 cites W1992425469 @default.
• W145418268 cites W1992506163 @default.
• W145418268 cites W1996365303 @default.
• W145418268 cites W1996805988 @default.
• W145418268 cites W2005934284 @default.
• W145418268 cites W2007253276 @default.
• W145418268 cites W2014951681 @default.
• W145418268 cites W2020229432 @default.
• W145418268 cites W2020625292 @default.
• W145418268 cites W2025018535 @default.
• W145418268 cites W2025572299 @default.
• W145418268 cites W2026477506 @default.
• W145418268 cites W2031142145 @default.
• W145418268 cites W2038750138 @default.
• W145418268 cites W2043117244 @default.
• W145418268 cites W2048861137 @default.
• W145418268 cites W2050568232 @default.
• W145418268 cites W2051745045 @default.
• W145418268 cites W2051942264 @default.
• W145418268 cites W2053313289 @default.
• W145418268 cites W2054044627 @default.
• W145418268 cites W2054233827 @default.
• W145418268 cites W2054708937 @default.
• W145418268 cites W2062744471 @default.
• W145418268 cites W20628388 @default.
• W145418268 cites W2063530769 @default.
• W145418268 cites W2064300486 @default.
• W145418268 cites W2072995607 @default.
• W145418268 cites W2073088363 @default.
• W145418268 cites W2073694156 @default.
• W145418268 cites W2077984737 @default.
• W145418268 cites W2079056854 @default.
• W145418268 cites W2081733578 @default.
• W145418268 cites W2082066412 @default.
• W145418268 cites W2082975940 @default.
• W145418268 cites W2084997952 @default.
• W145418268 cites W2086600457 @default.
• W145418268 cites W2088333322 @default.
• W145418268 cites W2088828540 @default.
• W145418268 cites W2094348636 @default.
• W145418268 cites W2101318220 @default.
• W145418268 cites W2104512614 @default.
• W145418268 cites W2123171103 @default.
• W145418268 cites W2131744664 @default.
• W145418268 cites W2161602614 @default.
• W145418268 cites W3146714045 @default.
• W145418268 cites W37222717 @default.
• W145418268 cites W4253990933 @default.
• W145418268 cites W611533236 @default.
• W145418268 doi "https://doi.org/10.1007/978-1-4615-4861-4_17" @default.
• W145418268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10086194" @default.
• W145418268 hasPublicationYear "1999" @default.
• W145418268 type Work @default.
• W145418268 sameAs 145418268 @default.
• W145418268 citedByCount "39" @default.
• W145418268 countsByYear W1454182682012 @default.
• W145418268 countsByYear W1454182682013 @default.
• W145418268 countsByYear W1454182682014 @default.
• W145418268 countsByYear W1454182682015 @default.
• W145418268 countsByYear W1454182682016 @default.
• W145418268 countsByYear W1454182682017 @default.
• W145418268 countsByYear W1454182682018 @default.
• W145418268 countsByYear W1454182682019 @default.
• W145418268 countsByYear W1454182682020 @default.
• W145418268 countsByYear W1454182682021 @default.
• W145418268 countsByYear W1454182682022 @default.
• W145418268 countsByYear W1454182682023 @default.
• W145418268 crossrefType "book-chapter" @default.
• W145418268 hasAuthorship W145418268A5044817021 @default.
• W145418268 hasAuthorship W145418268A5046194281 @default.
• W145418268 hasConcept C121608353 @default.
• W145418268 hasConcept C123012128 @default.
• W145418268 hasConcept C1491633281 @default.

• next