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- W1454813595 abstract "Despite the advanced modern biotechniques, thrombosis and bacterial infection of biomedical devices remain common complications that are associated with morbidity and mortality. Most antifouling surfaces are in solid form and cannot simultaneously fulfill the requirements for antithrombosis and antibacterial efficacy. In this work, we present a facile strategy to fabricate a slippery surface. This surface is created by combining photografting polymerization with osmotically driven wrinkling that can generate a coarse morphology, and followed by infusing with fluorocarbon liquid. The lubricant-infused wrinkling slippery surface can greatly prevent protein attachment, reduce platelet adhesion, and suppress thrombus formation in vitro. Furthermore, E. coli and S. aureus attachment on the slippery surfaces is reduced by ∼98.8% and ∼96.9% after 24 h incubation, relative to poly(styrene-b-isobutylene-b-styrene) (SIBS) references. This slippery surface is biocompatible and has no toxicity to L929 cells. This surface-coating strategy that effectively reduces thrombosis and the incidence of infection will greatly decrease healthcare costs." @default.
- W1454813595 created "2016-06-24" @default.
- W1454813595 creator A5005675580 @default.
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- W1454813595 date "2015-08-20" @default.
- W1454813595 modified "2023-10-14" @default.
- W1454813595 title "Facile Fabrication of Lubricant-Infused Wrinkling Surface for Preventing Thrombus Formation and Infection" @default.
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- W1454813595 doi "https://doi.org/10.1021/acsami.5b05865" @default.
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