Matches in SemOpenAlex for { <https://semopenalex.org/work/W1455041310> ?p ?o ?g. }
- W1455041310 endingPage "100" @default.
- W1455041310 startingPage "81" @default.
- W1455041310 abstract "This chapter focuses on the contribution of structural biology to the understanding of the type IV pili. Recent reviews cover the developments in research on molecular genetics, regulation of expression and assembly, pilus-mediated surface motility, host responses to pili, and pilus-based vaccines carried out by many laboratories around the world. High-resolution structures of four type IV pilins have been published. In the chapter, the structural details of each pilin subunit are elaborated and compared. Models for pilus filament assembly based on the monomer structures are also discussed. The limited structural information available for pilus assembly proteins is summarized. The chapter is an appropriate venue in which to clarify that type IV pilus filament models are not refined atomic resolution structures of pilus quatenary assemblies. To increase the accuracy and resolution of any type IV pilus assembly model, the model must be rigorously refined against moderate-resolution data for intact pili, such as cryoelectron microscopy reconstructions or complete high-resolution fiber diffraction data sets. These have been challenging to obtain for the very smooth and thin type IV pili. X-ray crystallography on additional pilin subunits, high-resolution electron microscopy reconstructions of intact pilus filaments, and structural biology of additional proteins in the type IV pilus pathway are clearly important next steps for understanding the mechanisms of pilus assembly, retraction, and function." @default.
- W1455041310 created "2016-06-24" @default.
- W1455041310 creator A5047644106 @default.
- W1455041310 date "2014-04-08" @default.
- W1455041310 modified "2023-09-23" @default.
- W1455041310 title "Structure and Assembly of Type IV Pilins" @default.
- W1455041310 cites W1502937395 @default.
- W1455041310 cites W1527241561 @default.
- W1455041310 cites W1581442411 @default.
- W1455041310 cites W1592897547 @default.
- W1455041310 cites W1596856256 @default.
- W1455041310 cites W1608164084 @default.
- W1455041310 cites W1763144417 @default.
- W1455041310 cites W1777736851 @default.
- W1455041310 cites W1844213024 @default.
- W1455041310 cites W1883721796 @default.
- W1455041310 cites W1921408963 @default.
- W1455041310 cites W1969886111 @default.
- W1455041310 cites W1972449088 @default.
- W1455041310 cites W1980858150 @default.
- W1455041310 cites W1983410419 @default.
- W1455041310 cites W1986953176 @default.
- W1455041310 cites W1988371610 @default.
- W1455041310 cites W1989393852 @default.
- W1455041310 cites W1991846211 @default.
- W1455041310 cites W1994921384 @default.
- W1455041310 cites W1997577186 @default.
- W1455041310 cites W2004621427 @default.
- W1455041310 cites W2007343241 @default.
- W1455041310 cites W2011581454 @default.
- W1455041310 cites W2016158447 @default.
- W1455041310 cites W2018893239 @default.
- W1455041310 cites W2019500447 @default.
- W1455041310 cites W2019758454 @default.
- W1455041310 cites W2020956640 @default.
- W1455041310 cites W2021410910 @default.
- W1455041310 cites W2021862499 @default.
- W1455041310 cites W2022762682 @default.
- W1455041310 cites W2029628243 @default.
- W1455041310 cites W2039768324 @default.
- W1455041310 cites W2040064814 @default.
- W1455041310 cites W2040838669 @default.
- W1455041310 cites W2049236474 @default.
- W1455041310 cites W2050930538 @default.
- W1455041310 cites W2060772988 @default.
- W1455041310 cites W2060837820 @default.
- W1455041310 cites W2061440509 @default.
- W1455041310 cites W2063741440 @default.
- W1455041310 cites W2065495830 @default.
- W1455041310 cites W2069953906 @default.
- W1455041310 cites W2071075943 @default.
- W1455041310 cites W2072260227 @default.
- W1455041310 cites W2083498141 @default.
- W1455041310 cites W2094068486 @default.
- W1455041310 cites W2105163513 @default.
- W1455041310 cites W2105177933 @default.
- W1455041310 cites W2106025487 @default.
- W1455041310 cites W2109588427 @default.
- W1455041310 cites W2110160301 @default.
- W1455041310 cites W2111719241 @default.
- W1455041310 cites W2111963409 @default.
- W1455041310 cites W2112662742 @default.
- W1455041310 cites W2115500377 @default.
- W1455041310 cites W2117217620 @default.
- W1455041310 cites W2122895999 @default.
- W1455041310 cites W2124704072 @default.
- W1455041310 cites W2128927528 @default.
- W1455041310 cites W2133966658 @default.
- W1455041310 cites W2134808133 @default.
- W1455041310 cites W2135147334 @default.
- W1455041310 cites W2140040046 @default.
- W1455041310 cites W2142648753 @default.
- W1455041310 cites W2144200388 @default.
- W1455041310 cites W2151600460 @default.
- W1455041310 cites W2152073656 @default.
- W1455041310 cites W2154873942 @default.
- W1455041310 cites W2159308541 @default.
- W1455041310 cites W2164263567 @default.
- W1455041310 cites W2167084558 @default.
- W1455041310 cites W2167870198 @default.
- W1455041310 cites W58301220 @default.
- W1455041310 doi "https://doi.org/10.1128/9781555818395.ch6" @default.
- W1455041310 hasPublicationYear "2014" @default.
- W1455041310 type Work @default.
- W1455041310 sameAs 1455041310 @default.
- W1455041310 citedByCount "2" @default.
- W1455041310 crossrefType "book-chapter" @default.
- W1455041310 hasAuthorship W1455041310A5047644106 @default.
- W1455041310 hasConcept C70721500 @default.
- W1455041310 hasConcept C86803240 @default.
- W1455041310 hasConcept C89423630 @default.
- W1455041310 hasConceptScore W1455041310C70721500 @default.
- W1455041310 hasConceptScore W1455041310C86803240 @default.
- W1455041310 hasConceptScore W1455041310C89423630 @default.
- W1455041310 hasLocation W14550413101 @default.
- W1455041310 hasOpenAccess W1455041310 @default.
- W1455041310 hasPrimaryLocation W14550413101 @default.
- W1455041310 hasRelatedWork W1641042124 @default.