Matches in SemOpenAlex for { <https://semopenalex.org/work/W1455496788> ?p ?o ?g. }
- W1455496788 abstract "High expression of matrix metalloproteinase-9 (MMP-9) was found to be correlated with tumor progression and poor prognosis in a variety of carcinomas. However, few studies have investigated the role of MMP-9 in human hilar cholangiocarcinoma. In this study, a total of 58 patients with hilar cholangiocarcinoma who underwent curative resection were included in this study. The expression of MMP-9 was analyzed by immunohistochemistry using the streptavidin peroxidase complex method. The correlation of MMP-9 overexpression with clinicopathological features and survival time of patients was investigated. The results showed that MMP-9 overexpression was prominent in cancer cells and mainly localized in the cytoplasm. MMP-9 overexpression was observed in 46.5% tumors, which showed no correlation with clinicopathological parameters. Patients with high MMP-9 expression had a significantly poorer overall survival rate than those with negative or low MMP-9 expression (P = 0.038). Multivariate analysis confirmed that MMP-9 overexpression was an independent prognostic factor (P = 0.007). In conclusion, overexpression of MMP-9 is a valuable independent prognostic indicator in hilar cholangiocarcinoma." @default.
- W1455496788 created "2016-06-24" @default.
- W1455496788 creator A5013988585 @default.
- W1455496788 creator A5034133337 @default.
- W1455496788 creator A5042712443 @default.
- W1455496788 creator A5045406516 @default.
- W1455496788 creator A5051964833 @default.
- W1455496788 creator A5053122964 @default.
- W1455496788 creator A5071348051 @default.
- W1455496788 creator A5080442910 @default.
- W1455496788 creator A5081256133 @default.
- W1455496788 date "2014-01-01" @default.
- W1455496788 modified "2023-09-26" @default.
- W1455496788 title "High expression of matrix metalloproteinase-9 indicates poor prognosis in human hilar cholangiocarcinoma." @default.
- W1455496788 cites W117431315 @default.
- W1455496788 cites W1574172480 @default.
- W1455496788 cites W1581404300 @default.
- W1455496788 cites W1886431664 @default.
- W1455496788 cites W1965938576 @default.
- W1455496788 cites W1971244052 @default.
- W1455496788 cites W1986884128 @default.
- W1455496788 cites W1991058402 @default.
- W1455496788 cites W1998680480 @default.
- W1455496788 cites W2001041467 @default.
- W1455496788 cites W2005530962 @default.
- W1455496788 cites W2006292968 @default.
- W1455496788 cites W2012409596 @default.
- W1455496788 cites W2013524931 @default.
- W1455496788 cites W2016944436 @default.
- W1455496788 cites W2022518765 @default.
- W1455496788 cites W2022687069 @default.
- W1455496788 cites W2040088523 @default.
- W1455496788 cites W2051543380 @default.
- W1455496788 cites W2087233429 @default.
- W1455496788 cites W2089260591 @default.
- W1455496788 cites W2094724339 @default.
- W1455496788 cites W2098576665 @default.
- W1455496788 cites W2099823824 @default.
- W1455496788 cites W2101496219 @default.
- W1455496788 cites W2103437429 @default.
- W1455496788 cites W2106814226 @default.
- W1455496788 cites W2107561601 @default.
- W1455496788 cites W2107948751 @default.
- W1455496788 cites W2108679528 @default.
- W1455496788 cites W2117980967 @default.
- W1455496788 cites W2146278165 @default.
- W1455496788 cites W2160755225 @default.
- W1455496788 cites W2409830569 @default.
- W1455496788 cites W2465779665 @default.
- W1455496788 cites W30449607 @default.
- W1455496788 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4203235" @default.
- W1455496788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25337264" @default.
- W1455496788 hasPublicationYear "2014" @default.
- W1455496788 type Work @default.
- W1455496788 sameAs 1455496788 @default.
- W1455496788 citedByCount "13" @default.
- W1455496788 countsByYear W14554967882015 @default.
- W1455496788 countsByYear W14554967882016 @default.
- W1455496788 countsByYear W14554967882018 @default.
- W1455496788 countsByYear W14554967882019 @default.
- W1455496788 countsByYear W14554967882020 @default.
- W1455496788 countsByYear W14554967882021 @default.
- W1455496788 countsByYear W14554967882022 @default.
- W1455496788 crossrefType "journal-article" @default.
- W1455496788 hasAuthorship W1455496788A5013988585 @default.
- W1455496788 hasAuthorship W1455496788A5034133337 @default.
- W1455496788 hasAuthorship W1455496788A5042712443 @default.
- W1455496788 hasAuthorship W1455496788A5045406516 @default.
- W1455496788 hasAuthorship W1455496788A5051964833 @default.
- W1455496788 hasAuthorship W1455496788A5053122964 @default.
- W1455496788 hasAuthorship W1455496788A5071348051 @default.
- W1455496788 hasAuthorship W1455496788A5080442910 @default.
- W1455496788 hasAuthorship W1455496788A5081256133 @default.
- W1455496788 hasConcept C109523444 @default.
- W1455496788 hasConcept C121608353 @default.
- W1455496788 hasConcept C126322002 @default.
- W1455496788 hasConcept C142724271 @default.
- W1455496788 hasConcept C204232928 @default.
- W1455496788 hasConcept C2991819120 @default.
- W1455496788 hasConcept C502942594 @default.
- W1455496788 hasConcept C71924100 @default.
- W1455496788 hasConcept C86803240 @default.
- W1455496788 hasConcept C90924648 @default.
- W1455496788 hasConceptScore W1455496788C109523444 @default.
- W1455496788 hasConceptScore W1455496788C121608353 @default.
- W1455496788 hasConceptScore W1455496788C126322002 @default.
- W1455496788 hasConceptScore W1455496788C142724271 @default.
- W1455496788 hasConceptScore W1455496788C204232928 @default.
- W1455496788 hasConceptScore W1455496788C2991819120 @default.
- W1455496788 hasConceptScore W1455496788C502942594 @default.
- W1455496788 hasConceptScore W1455496788C71924100 @default.
- W1455496788 hasConceptScore W1455496788C86803240 @default.
- W1455496788 hasConceptScore W1455496788C90924648 @default.
- W1455496788 hasLocation W14554967881 @default.
- W1455496788 hasOpenAccess W1455496788 @default.
- W1455496788 hasPrimaryLocation W14554967881 @default.
- W1455496788 hasRelatedWork W1606743061 @default.
- W1455496788 hasRelatedWork W2043310346 @default.
- W1455496788 hasRelatedWork W2044865671 @default.
- W1455496788 hasRelatedWork W2047260073 @default.