FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1457564736> ?p ?o ?g. }

• W1457564736 abstract "Correct typing of donors’ and recipients’ blood group is of paramount importance in transfusion services. There are two distinct parts in ABO typing, forward and reverse typing, both of which are routinely carried out1. Reverse typing is obligatory, because it can help to reveal mistyping, weak A subgroups with anti-A1 and unexpected IgM antibodies. Any discrepancy between the results of the tests with serum or plasma and red cells should be investigated. Reverse grouping cells, including A, B, O and A2 type red blood cells (RBC), are important to resolve ABO discrepancies. Anti-A and/or anti-B antibodies can be easily detected by red blood cells with A and/or B blood group antigens. The presence of an anti-A1 should be confirmed by testing serum against A1, A2, and O red cells. This method necessitates A2 reverse grouping cells. Very few people in China have the A2 blood group. In the Xi’an area (north-western China) only about 0.0006% of the population have A2 RBC, while about 0.003% of the population have the A2B group are. The ratio of the prevalence of A2B:A2 is 5 (unpublished data). In the Shanghai area (eastern China), this same ratio is about 2.5. Thus, there are more people with A2B group RBC than there are with A2 RBC2,3. As it is known that α-galactosidase, a kind of exoglycosidase, can remove the reducing end α-galactose residues of group B antigen by hydrolysis and based on the characteristics of the group B epitopes and α-galactosidase hydrolysis reaction, α-galactosidase has been used in B to O RBC conversion study since the 1980s4. Our group has been researching in this area for more than 10 years5,6 and we recently obtained a novel α-galactosidase from B. fragilis (which belong to CAZy GH110) with highly specific activity, greatly restricted substrate specificity and a neutral pH optimum7,8. Our research showed that this novel α-galactosidase can convert B RBC to O RBC with high substrate specificity and at low cost7,8. We, therefore, started to study the A2B to A2 conversion using α-galactosidase in order to broaden the source of A2 RBC." @default.
• W1457564736 created "2016-06-24" @default.
• W1457564736 creator A5003152439 @default.
• W1457564736 creator A5003395715 @default.
• W1457564736 creator A5018349567 @default.
• W1457564736 creator A5018766522 @default.
• W1457564736 creator A5023984980 @default.
• W1457564736 creator A5041249930 @default.
• W1457564736 creator A5065240546 @default.
• W1457564736 creator A5071249790 @default.
• W1457564736 creator A5084197725 @default.
• W1457564736 creator A5090015629 @default.
• W1457564736 date "2013-04-01" @default.
• W1457564736 modified "2023-09-25" @default.
• W1457564736 title "Preparation of A2 reverse grouping cells from A2B red blood cells by alpha-galactosidase." @default.
• W1457564736 cites W1995140263 @default.
• W1457564736 cites W2020218579 @default.
• W1457564736 cites W2056767067 @default.
• W1457564736 cites W2094505501 @default.
• W1457564736 cites W2145949970 @default.
• W1457564736 cites W2357943864 @default.
• W1457564736 cites W2360677847 @default.
• W1457564736 cites W2404303409 @default.
• W1457564736 doi "https://doi.org/10.2450/2012.0020-12" @default.
• W1457564736 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3626484" @default.
• W1457564736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23149135" @default.
• W1457564736 hasPublicationYear "2013" @default.
• W1457564736 type Work @default.
• W1457564736 sameAs 1457564736 @default.
• W1457564736 citedByCount "1" @default.
• W1457564736 countsByYear W14575647362016 @default.
• W1457564736 crossrefType "journal-article" @default.
• W1457564736 hasAuthorship W1457564736A5003152439 @default.
• W1457564736 hasAuthorship W1457564736A5003395715 @default.
• W1457564736 hasAuthorship W1457564736A5018349567 @default.
• W1457564736 hasAuthorship W1457564736A5018766522 @default.
• W1457564736 hasAuthorship W1457564736A5023984980 @default.
• W1457564736 hasAuthorship W1457564736A5041249930 @default.
• W1457564736 hasAuthorship W1457564736A5065240546 @default.
• W1457564736 hasAuthorship W1457564736A5071249790 @default.
• W1457564736 hasAuthorship W1457564736A5084197725 @default.
• W1457564736 hasAuthorship W1457564736A5090015629 @default.
• W1457564736 hasConcept C126322002 @default.
• W1457564736 hasConcept C147483822 @default.
• W1457564736 hasConcept C153911025 @default.
• W1457564736 hasConcept C159654299 @default.
• W1457564736 hasConcept C176080213 @default.
• W1457564736 hasConcept C184113351 @default.
• W1457564736 hasConcept C195616568 @default.
• W1457564736 hasConcept C203014093 @default.
• W1457564736 hasConcept C2776557347 @default.
• W1457564736 hasConcept C2777208419 @default.
• W1457564736 hasConcept C2781209916 @default.
• W1457564736 hasConcept C2908647359 @default.
• W1457564736 hasConcept C54355233 @default.
• W1457564736 hasConcept C71924100 @default.
• W1457564736 hasConcept C86803240 @default.
• W1457564736 hasConcept C99454951 @default.
• W1457564736 hasConceptScore W1457564736C126322002 @default.
• W1457564736 hasConceptScore W1457564736C147483822 @default.
• W1457564736 hasConceptScore W1457564736C153911025 @default.
• W1457564736 hasConceptScore W1457564736C159654299 @default.
• W1457564736 hasConceptScore W1457564736C176080213 @default.
• W1457564736 hasConceptScore W1457564736C184113351 @default.
• W1457564736 hasConceptScore W1457564736C195616568 @default.
• W1457564736 hasConceptScore W1457564736C203014093 @default.
• W1457564736 hasConceptScore W1457564736C2776557347 @default.
• W1457564736 hasConceptScore W1457564736C2777208419 @default.
• W1457564736 hasConceptScore W1457564736C2781209916 @default.
• W1457564736 hasConceptScore W1457564736C2908647359 @default.
• W1457564736 hasConceptScore W1457564736C54355233 @default.
• W1457564736 hasConceptScore W1457564736C71924100 @default.
• W1457564736 hasConceptScore W1457564736C86803240 @default.
• W1457564736 hasConceptScore W1457564736C99454951 @default.
• W1457564736 hasLocation W14575647361 @default.
• W1457564736 hasOpenAccess W1457564736 @default.
• W1457564736 hasPrimaryLocation W14575647361 @default.
• W1457564736 hasRelatedWork W1541738353 @default.
• W1457564736 hasRelatedWork W1583834935 @default.
• W1457564736 hasRelatedWork W1747937511 @default.
• W1457564736 hasRelatedWork W1968710892 @default.
• W1457564736 hasRelatedWork W1987941332 @default.
• W1457564736 hasRelatedWork W19969561 @default.
• W1457564736 hasRelatedWork W2016077314 @default.
• W1457564736 hasRelatedWork W2034432030 @default.
• W1457564736 hasRelatedWork W2072123454 @default.
• W1457564736 hasRelatedWork W2088249236 @default.
• W1457564736 hasRelatedWork W2103036318 @default.
• W1457564736 hasRelatedWork W2115483140 @default.
• W1457564736 hasRelatedWork W2264417208 @default.
• W1457564736 hasRelatedWork W2276004569 @default.
• W1457564736 hasRelatedWork W2404303409 @default.
• W1457564736 hasRelatedWork W2429238941 @default.
• W1457564736 hasRelatedWork W2496695354 @default.
• W1457564736 hasRelatedWork W2796423097 @default.
• W1457564736 hasRelatedWork W2911657790 @default.
• W1457564736 hasRelatedWork W3147035665 @default.
• W1457564736 isParatext "false" @default.
• W1457564736 isRetracted "false" @default.
• W1457564736 magId "1457564736" @default.

• next