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- W145840508 abstract "In 1924, Major Greenwood [1] stated in The Lancet that ‘there is a kind of statistical tact, which is rather more than simple good sense; some are born with it; … the rest of us have to acquire it.’ There are three principal areas of clinical trials in which one can demonstrate such statistical tact: designing a study, analyzing the results of a study, and synthesizing the medical literature. There have been many medical articles [2, 3, 4, 5, 6, 7, 8], chapters of oncology texts [9, 10, 11], books on clinical trials [12, 13, 14, 15], and introductory biostatistics texts [16, 17, 18, 19, 20, 21] that cover many subtopics in these three areas. In this chapter only three subtopics will be discussed: subgroups, competing risks, and meta-analysis. These three subtopics are more frequently mentioned in adjuvant breast cancer articles than in articles on metastatic breast cancer or other types of cancer. Hence they provide special opportunities for investigators of early breast cancer to display statistical tact." @default.
- W145840508 created "2016-06-24" @default.
- W145840508 creator A5062329369 @default.
- W145840508 date "1992-01-01" @default.
- W145840508 modified "2023-09-27" @default.
- W145840508 title "Statistical methods for early breast cancer trials" @default.
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- W145840508 doi "https://doi.org/10.1007/978-1-4615-3496-9_2" @default.
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