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- W1463809069 abstract "Recent diagnostic and therapeutic advances have propelled the galactorrhea-amenorrhea syndrome to the forefront of medical awareness and many more cases of pituitary prolactinemia are being diagnosed treated and reported. But the increase cited in this editorial goes beyond refinement of diagnositic tests; other factors are cited as causing a real increased incidence. 1 factor is the use of estrogen-containing oral contraceptives. In a series of 30 patients with galactorrhea and amenorrhea 23 had hyperprolactinemia. In 19 of these symptoms followed the use of oral contraceptives and in 4 they appeared after parturition. 3/19 had radiographic evidence of a pituitary tumor. A temporal link between the manifestations of prolactinemia and oral contraceptive use or childbirth is evident in a series of 42 patients with amenorrhea-galactorrhea and hyperprolactinemia who underwnet transsphenoidal resection of histologically verified pituitary adenomas. In 31 of these patients symptoms developed in close association with the use or discontinued use of oral contraceptives or after childbirth. Therefore estrogens are thought to promote growth of preexisting silent pituitary lesions." @default.
- W1463809069 created "2016-06-24" @default.
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- W1463809069 date "1979-07-13" @default.
- W1463809069 modified "2023-09-23" @default.
- W1463809069 title "Pituitary prolactinoma and estrogen contraceptives. (Editorial)" @default.
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