Matches in SemOpenAlex for { <https://semopenalex.org/work/W146480224> ?p ?o ?g. }
- W146480224 endingPage "81" @default.
- W146480224 startingPage "49" @default.
- W146480224 abstract "Experimental allergic neuritis (EAN), an experimental model of GBS, developed as a by-product of research into experimental allergic encephalomyelitis (EAE). In 1895 Louis Pasteur had prepared the first rabies vaccines from dried formalin-treated rabbit brain. The vaccine provided some protection from rabies but also occasionally caused encephalomyelitis. Rivers and Schwentker (1935) showed that repeated injections of rabbit brain into monkeys would produce encephalomyelitis and Freund in 1949 showed that the same result could be achieved with a single injection provided that the nervous tissue was emulsified with an adjuvant. Early experiments were directed towards identifying the antigen. The encephalitogenic component of nervous tissue was found to reside largely in the major myelin basic protein (see Leibowitz and Hughes 1983 for review). More recently it has been demonstrated that highly purified proteolipid protein will also induce EAE (Yoshimura et al. 1985; Endoh et al. 1986). There is no theoretical reason why other CNS myelin antigens should not be capable of inducing EAE. Myelin basic protein (MBP), molecular weight 18 500, is rich in basic aminoacids, and its amino acid sequence is highly conserved from one species to another (Hashim 1980). However, there is great species variation in the part of the protein which is responsible for inducing EAE." @default.
- W146480224 created "2016-06-24" @default.
- W146480224 creator A5049139387 @default.
- W146480224 date "1990-01-01" @default.
- W146480224 modified "2023-09-26" @default.
- W146480224 title "Experimental Allergic Neuritis" @default.
- W146480224 cites W1486146823 @default.
- W146480224 cites W1492083940 @default.
- W146480224 cites W1512511436 @default.
- W146480224 cites W1534891167 @default.
- W146480224 cites W1554618165 @default.
- W146480224 cites W1569519000 @default.
- W146480224 cites W1587724111 @default.
- W146480224 cites W1600746557 @default.
- W146480224 cites W1604116489 @default.
- W146480224 cites W1955068511 @default.
- W146480224 cites W1963493337 @default.
- W146480224 cites W1965197866 @default.
- W146480224 cites W1965893013 @default.
- W146480224 cites W1966577570 @default.
- W146480224 cites W1966710505 @default.
- W146480224 cites W1968801526 @default.
- W146480224 cites W1969851838 @default.
- W146480224 cites W1970560263 @default.
- W146480224 cites W1970798087 @default.
- W146480224 cites W1973549279 @default.
- W146480224 cites W1974357433 @default.
- W146480224 cites W1975230863 @default.
- W146480224 cites W1976249117 @default.
- W146480224 cites W1977462785 @default.
- W146480224 cites W1977854868 @default.
- W146480224 cites W1978689177 @default.
- W146480224 cites W1979642651 @default.
- W146480224 cites W1980416825 @default.
- W146480224 cites W1982582854 @default.
- W146480224 cites W1983325662 @default.
- W146480224 cites W1985700025 @default.
- W146480224 cites W1988250530 @default.
- W146480224 cites W1989085668 @default.
- W146480224 cites W1989476533 @default.
- W146480224 cites W1993928359 @default.
- W146480224 cites W1994624515 @default.
- W146480224 cites W1995632735 @default.
- W146480224 cites W1997138234 @default.
- W146480224 cites W1998699294 @default.
- W146480224 cites W2000768433 @default.
- W146480224 cites W2001496309 @default.
- W146480224 cites W2002508428 @default.
- W146480224 cites W2005375725 @default.
- W146480224 cites W2005946184 @default.
- W146480224 cites W2006452021 @default.
- W146480224 cites W2008127759 @default.
- W146480224 cites W2008272481 @default.
- W146480224 cites W2008577107 @default.
- W146480224 cites W2011436130 @default.
- W146480224 cites W2013387515 @default.
- W146480224 cites W2014077811 @default.
- W146480224 cites W2017243368 @default.
- W146480224 cites W2017644220 @default.
- W146480224 cites W2018914987 @default.
- W146480224 cites W2023345384 @default.
- W146480224 cites W2024156557 @default.
- W146480224 cites W2025461622 @default.
- W146480224 cites W2026730273 @default.
- W146480224 cites W2028803131 @default.
- W146480224 cites W2031378677 @default.
- W146480224 cites W2031538716 @default.
- W146480224 cites W2031633405 @default.
- W146480224 cites W2033595537 @default.
- W146480224 cites W2033661628 @default.
- W146480224 cites W2034318072 @default.
- W146480224 cites W2035715363 @default.
- W146480224 cites W2036463478 @default.
- W146480224 cites W2038862891 @default.
- W146480224 cites W2039365814 @default.
- W146480224 cites W2039650869 @default.
- W146480224 cites W2040439317 @default.
- W146480224 cites W2040606739 @default.
- W146480224 cites W2042270291 @default.
- W146480224 cites W2044158555 @default.
- W146480224 cites W2044578153 @default.
- W146480224 cites W2044757149 @default.
- W146480224 cites W2045659510 @default.
- W146480224 cites W2049729456 @default.
- W146480224 cites W2052759614 @default.
- W146480224 cites W2054698161 @default.
- W146480224 cites W2055690558 @default.
- W146480224 cites W2055859439 @default.
- W146480224 cites W2056604096 @default.
- W146480224 cites W2057367268 @default.
- W146480224 cites W2058992205 @default.
- W146480224 cites W2061008206 @default.
- W146480224 cites W2064289703 @default.
- W146480224 cites W2064390120 @default.
- W146480224 cites W2066744810 @default.
- W146480224 cites W2069082536 @default.
- W146480224 cites W2069470155 @default.
- W146480224 cites W2073480889 @default.