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- W146595787 abstract "Generalized dysfunction of the vascular endothelium, that leads to edema formation and ARDS, is in large part a result of the action of proteases and oxygen radicals that are released from activated neutrophils [1], Bacterial products such as fMPL, complement activation products, in particular C5a, and lipid mediators including platelet activating factor (PAF), are all potent neutrophil activators. Cytokines, such as tumor necrosis factor (TNF), are also know to importantly stimulate neutrophils. In this chapter, we will discuss the potential role of a neutrophil-activating cytokine, interleukin-8 (IL-8), that is a low molecular weight protein belonging to the chemokine family (also known as small cytokine -SCY-family), in sepsis." @default.
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- W146595787 date "1993-01-01" @default.
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- W146595787 title "Potential Importance of IL-8: A Potent Chemokine, in Sepsis" @default.
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- W146595787 doi "https://doi.org/10.1007/978-3-642-84904-6_11" @default.
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