Matches in SemOpenAlex for { <https://semopenalex.org/work/W146596565> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W146596565 abstract "Suppositories are important tools for individual therapy, especially in paediatrics, and an instrumental assay method has become necessary for the quality control of dosage units. The aim of this work was to develop a rapid, effective high-performance liquid chromatography method to assay aminophenazone in extemporaneous suppositories prepared with two different suppository bases, adeps solidus and massa macrogoli. With a novel sample preparation method developed by the authors, 4-dimethylaminoantipyrine was determined in these suppository bases with 95-105% recovery. The measurements were carried out on a Shimadzu Prominence ultra high-performance liquid chromatography system equipped with a 20 μl sample loop. The separation was achieved on a Hypersil ODS column, with methanol, sodium acetate buffer (pH 5.5±0.05, 0.05 M, 60:40, v/v) as the mobile phase at a flow rate of 1.5 ml/min. The chromatograms were acquired at 253 nm. The chromatographic method was fully validated in accordance with current guidelines. The presented data demonstrate the successful development of a rapid, efficient and robust sample preparation and high-performance liquid chromatography method for the routine quality control of the dosage units of suppositories containing 4-dimethylaminoantipyrine." @default.
- W146596565 created "2016-06-24" @default.
- W146596565 creator A5000013561 @default.
- W146596565 creator A5012574780 @default.
- W146596565 creator A5057194119 @default.
- W146596565 creator A5057769318 @default.
- W146596565 date "2014-01-01" @default.
- W146596565 modified "2023-09-23" @default.
- W146596565 title "Validated HPLC determination of 4-dimethylaminoantipyrine in different suppository bases." @default.
- W146596565 cites W139291788 @default.
- W146596565 cites W1534392512 @default.
- W146596565 cites W1541515816 @default.
- W146596565 cites W156188999 @default.
- W146596565 cites W1991523545 @default.
- W146596565 cites W1998452839 @default.
- W146596565 cites W2000524760 @default.
- W146596565 cites W2005470532 @default.
- W146596565 cites W2014051487 @default.
- W146596565 cites W2020346012 @default.
- W146596565 cites W2025983377 @default.
- W146596565 cites W2033135742 @default.
- W146596565 cites W2057595608 @default.
- W146596565 cites W2065209479 @default.
- W146596565 cites W2067329010 @default.
- W146596565 cites W2075647533 @default.
- W146596565 cites W2078504241 @default.
- W146596565 cites W2079699599 @default.
- W146596565 cites W2085239986 @default.
- W146596565 cites W2094789700 @default.
- W146596565 cites W2102230314 @default.
- W146596565 cites W2110262679 @default.
- W146596565 cites W2133744605 @default.
- W146596565 cites W2136534065 @default.
- W146596565 cites W2291882178 @default.
- W146596565 cites W277290643 @default.
- W146596565 cites W49042587 @default.
- W146596565 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4007253" @default.
- W146596565 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24799736" @default.
- W146596565 hasPublicationYear "2014" @default.
- W146596565 type Work @default.
- W146596565 sameAs 146596565 @default.
- W146596565 citedByCount "1" @default.
- W146596565 countsByYear W1465965652015 @default.
- W146596565 crossrefType "journal-article" @default.
- W146596565 hasAuthorship W146596565A5000013561 @default.
- W146596565 hasAuthorship W146596565A5012574780 @default.
- W146596565 hasAuthorship W146596565A5057194119 @default.
- W146596565 hasAuthorship W146596565A5057769318 @default.
- W146596565 hasConcept C179998833 @default.
- W146596565 hasConcept C185592680 @default.
- W146596565 hasConcept C2778042862 @default.
- W146596565 hasConcept C43617362 @default.
- W146596565 hasConcept C71924100 @default.
- W146596565 hasConcept C98274493 @default.
- W146596565 hasConceptScore W146596565C179998833 @default.
- W146596565 hasConceptScore W146596565C185592680 @default.
- W146596565 hasConceptScore W146596565C2778042862 @default.
- W146596565 hasConceptScore W146596565C43617362 @default.
- W146596565 hasConceptScore W146596565C71924100 @default.
- W146596565 hasConceptScore W146596565C98274493 @default.
- W146596565 hasLocation W1465965651 @default.
- W146596565 hasOpenAccess W146596565 @default.
- W146596565 hasPrimaryLocation W1465965651 @default.
- W146596565 hasRelatedWork W1965708119 @default.
- W146596565 hasRelatedWork W1974238950 @default.
- W146596565 hasRelatedWork W1989708172 @default.
- W146596565 hasRelatedWork W2022974133 @default.
- W146596565 hasRelatedWork W2076136042 @default.
- W146596565 hasRelatedWork W2086539092 @default.
- W146596565 hasRelatedWork W2158919331 @default.
- W146596565 hasRelatedWork W2171701132 @default.
- W146596565 hasRelatedWork W2186003100 @default.
- W146596565 hasRelatedWork W2186117578 @default.
- W146596565 hasRelatedWork W2187570963 @default.
- W146596565 hasRelatedWork W2462749749 @default.
- W146596565 hasRelatedWork W2554686893 @default.
- W146596565 hasRelatedWork W2739287288 @default.
- W146596565 hasRelatedWork W2901182269 @default.
- W146596565 hasRelatedWork W2910032644 @default.
- W146596565 hasRelatedWork W3023089600 @default.
- W146596565 hasRelatedWork W3087593951 @default.
- W146596565 hasRelatedWork W3134118291 @default.
- W146596565 hasRelatedWork W93896507 @default.
- W146596565 isParatext "false" @default.
- W146596565 isRetracted "false" @default.
- W146596565 magId "146596565" @default.
- W146596565 workType "article" @default.