Matches in SemOpenAlex for { <https://semopenalex.org/work/W146601371> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W146601371 endingPage "137" @default.
- W146601371 startingPage "132" @default.
- W146601371 abstract "Legionellae are opportunistic facultative intracellular pathogens with several antigens and toxic components which may function synergistically in contribution to pathogenesis and immunity. The serogroup specific antigens are associated with endotoxic activities of the bacteria and are potent adjuvants in inducing hypersensitivity and potentiating antibody responses to various antigens. Two protein toxins interfere with oxidative metabolism of host cells and are potential inhibitors of intracellular bactericidal activities. Tissue damage in the host appears to be caused by lysis of infected cells with release of toxic substances of host and bacterial origins. In host defense, the serogroup antigens provide primarily group-specific immunity, and the acid soluble protein toxin induces cross-protection among different serogroups. The combined effects of antibodies to these antigens in promoting phagocytosis and abrogating toxicity would enhance intracellular killing of the invading bacteria. The serogroup antigen complexes may also function as a potent adjuvant to modulate host responses to the invading bacteria." @default.
- W146601371 created "2016-06-24" @default.
- W146601371 creator A5006832675 @default.
- W146601371 creator A5031142115 @default.
- W146601371 date "1983-07-01" @default.
- W146601371 modified "2023-09-25" @default.
- W146601371 title "Antigens and Toxic Components of Legionella in Pathogenesis and Immunity" @default.
- W146601371 cites W1995615351 @default.
- W146601371 cites W2008201712 @default.
- W146601371 cites W2011817345 @default.
- W146601371 cites W2017629847 @default.
- W146601371 cites W2028703307 @default.
- W146601371 cites W2031542097 @default.
- W146601371 cites W2033639069 @default.
- W146601371 cites W2036431012 @default.
- W146601371 cites W2086254443 @default.
- W146601371 cites W2337740827 @default.
- W146601371 cites W4240528823 @default.
- W146601371 doi "https://doi.org/10.1016/s0174-3031(83)80043-2" @default.
- W146601371 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6637227" @default.
- W146601371 hasPublicationYear "1983" @default.
- W146601371 type Work @default.
- W146601371 sameAs 146601371 @default.
- W146601371 citedByCount "3" @default.
- W146601371 crossrefType "journal-article" @default.
- W146601371 hasAuthorship W146601371A5006832675 @default.
- W146601371 hasAuthorship W146601371A5031142115 @default.
- W146601371 hasConcept C147483822 @default.
- W146601371 hasConcept C153726182 @default.
- W146601371 hasConcept C159654299 @default.
- W146601371 hasConcept C160448771 @default.
- W146601371 hasConcept C203014093 @default.
- W146601371 hasConcept C2777863537 @default.
- W146601371 hasConcept C2779341262 @default.
- W146601371 hasConcept C523546767 @default.
- W146601371 hasConcept C54355233 @default.
- W146601371 hasConcept C79879829 @default.
- W146601371 hasConcept C86803240 @default.
- W146601371 hasConcept C8891405 @default.
- W146601371 hasConcept C89423630 @default.
- W146601371 hasConcept C95444343 @default.
- W146601371 hasConceptScore W146601371C147483822 @default.
- W146601371 hasConceptScore W146601371C153726182 @default.
- W146601371 hasConceptScore W146601371C159654299 @default.
- W146601371 hasConceptScore W146601371C160448771 @default.
- W146601371 hasConceptScore W146601371C203014093 @default.
- W146601371 hasConceptScore W146601371C2777863537 @default.
- W146601371 hasConceptScore W146601371C2779341262 @default.
- W146601371 hasConceptScore W146601371C523546767 @default.
- W146601371 hasConceptScore W146601371C54355233 @default.
- W146601371 hasConceptScore W146601371C79879829 @default.
- W146601371 hasConceptScore W146601371C86803240 @default.
- W146601371 hasConceptScore W146601371C8891405 @default.
- W146601371 hasConceptScore W146601371C89423630 @default.
- W146601371 hasConceptScore W146601371C95444343 @default.
- W146601371 hasIssue "1" @default.
- W146601371 hasLocation W1466013711 @default.
- W146601371 hasLocation W1466013712 @default.
- W146601371 hasOpenAccess W146601371 @default.
- W146601371 hasPrimaryLocation W1466013711 @default.
- W146601371 hasRelatedWork W163054691 @default.
- W146601371 hasRelatedWork W1782834361 @default.
- W146601371 hasRelatedWork W1887000714 @default.
- W146601371 hasRelatedWork W1993258464 @default.
- W146601371 hasRelatedWork W203949208 @default.
- W146601371 hasRelatedWork W2043416577 @default.
- W146601371 hasRelatedWork W2134281392 @default.
- W146601371 hasRelatedWork W2194280214 @default.
- W146601371 hasRelatedWork W2411458158 @default.
- W146601371 hasRelatedWork W2413765641 @default.
- W146601371 hasVolume "255" @default.
- W146601371 isParatext "false" @default.
- W146601371 isRetracted "false" @default.
- W146601371 magId "146601371" @default.
- W146601371 workType "article" @default.