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- W146637842 abstract "Publisher Summary The study of immunochemistry of enzymes has been interwoven in manifold research areas that are related to immunochemistry and enzymology. It has been of assistance also in the pursuit of several other problems that arise in contemporary biology; this chapter discusses several aspects of this research. In immunochemical investigations, and particularly in the study of the various parameters of the immune response on the molecular level, one of the paramount factors for which the enzymes have been used as an important vehicle is the elucidation of antigenic specificity determinants and their structural parameters. The use of enzymes as antigens, rather than other proteins, offers an advantage because the antigens possess biologic activity that resides in a limited area of the molecule, and antibodies specific toward this or related regions might have an effect on the catalytic activity. The contribution of different determinants to the immunologic reactivity of an enzyme can be evaluated in the light of their relationship to its catalytic site. Antibodies to specific enzymes can be employed in the search for enzymes of biologic pathways that disappeared in the course of evolution, or to detect the extent of similarity between enzymes that persisted through the ages." @default.
- W146637842 created "2016-06-24" @default.
- W146637842 creator A5080343326 @default.
- W146637842 date "1973-01-01" @default.
- W146637842 modified "2023-09-26" @default.
- W146637842 title "Immunochemistry of Enzymes" @default.
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