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• W146666970 abstract "Caspase inhibitors fail to prevent the programmed cell death (PCD) of developing motoneurons (MNs) in the chick embryo in ovo, and genetic deletion of upstream (caspase-9) or downstream (caspase-3) caspase family members in mice does not prevent the PCD of developing MNs or other populations of target-dependent post-mitotic neurons. Neurons undergoing PCD in the absence of caspases exhibit a non-apoptotic, often TUNEL-negative, mode of morphological degeneration. Loss of caspase activity may delay but does not prevent the quantitatively normal occurrence of neuronal PCD." @default.
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• W146666970 date "2001-01-01" @default.
• W146666970 modified "2023-09-26" @default.
• W146666970 title "Normal Programmed Cell Death of Developing Avian and Mammalian Neurons Following Inhibition or Genetic Deletion of Caspases" @default.
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• W146666970 doi "https://doi.org/10.1007/978-3-662-04333-2_6" @default.
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