Matches in SemOpenAlex for { <https://semopenalex.org/work/W1468706931> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1468706931 endingPage "709" @default.
- W1468706931 startingPage "702" @default.
- W1468706931 abstract "Because ursodeoxycholic and chenodeoxycholic acids are interconverted in humans via 7-ketolithocholic acid, bile acid metabolism was studied in the nutria (Myocastor coypus), the bile of which is known to contain these three bile acids. Relative concentrations of ursodeoxycholic (37% +/- 20%), 7-ketolithocholic (33% +/- 17%), and chenodeoxycholic (17% +/- 9%) acids in gallbladder bile were unchanged by 5-20 h of complete biliary diversion (n = 7). Injection of either [14C]cholesterol, [14C]ursodeoxycholic, [14C]7-ketolithocholic acid, or a mixture of [7 beta-3H]chenodeoxycholic acid and [14C]chenodeoxycholic acid into bile fistula nutria demonstrated that all three bile acids can be synthesized hepatically from cholesterol, that they are interconverted sparingly (2%-5%) by the liver, but that 7-ketolithocholic acid is an intermediate in the hepatic transformation of chenodeoxycholic acid to ursodeoxycholic acid. An animal that had been fed antibiotics showed an unusually elevated concentration of ursodeoxycholic acid in gallbladder and hepatic bile, suggesting that bacterial transformation of ursodeoxycholic acid in the intestine may be a source of some biliary chenodeoxycholic acid and 7-ketolithocholic acid." @default.
- W1468706931 created "2016-06-24" @default.
- W1468706931 creator A5004131447 @default.
- W1468706931 creator A5018794637 @default.
- W1468706931 creator A5088748837 @default.
- W1468706931 creator A5089441541 @default.
- W1468706931 creator A5090611425 @default.
- W1468706931 date "1986-03-01" @default.
- W1468706931 modified "2023-09-28" @default.
- W1468706931 title "Ursodeoxycholic Acid, 7-Ketolithocholic Acid, and Chenodeoxycholic Acid Are Primary Bile Acids of the Nutria (Myocastor copus)" @default.
- W1468706931 cites W1531658136 @default.
- W1468706931 cites W1584619265 @default.
- W1468706931 cites W1898967101 @default.
- W1468706931 cites W1940667593 @default.
- W1468706931 cites W194751745 @default.
- W1468706931 cites W2041289545 @default.
- W1468706931 cites W2049016611 @default.
- W1468706931 cites W2053351361 @default.
- W1468706931 cites W2058028226 @default.
- W1468706931 cites W2063813012 @default.
- W1468706931 cites W2068634846 @default.
- W1468706931 cites W2128821979 @default.
- W1468706931 cites W2131101159 @default.
- W1468706931 cites W2140211416 @default.
- W1468706931 cites W2154204081 @default.
- W1468706931 cites W2162719733 @default.
- W1468706931 cites W2168975531 @default.
- W1468706931 cites W2183996413 @default.
- W1468706931 cites W2185358847 @default.
- W1468706931 cites W2226168039 @default.
- W1468706931 cites W2297632339 @default.
- W1468706931 cites W2338113819 @default.
- W1468706931 cites W2343922474 @default.
- W1468706931 doi "https://doi.org/10.1016/0016-5085(86)91126-1" @default.
- W1468706931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3943698" @default.
- W1468706931 hasPublicationYear "1986" @default.
- W1468706931 type Work @default.
- W1468706931 sameAs 1468706931 @default.
- W1468706931 citedByCount "25" @default.
- W1468706931 countsByYear W14687069312013 @default.
- W1468706931 countsByYear W14687069312019 @default.
- W1468706931 countsByYear W14687069312021 @default.
- W1468706931 countsByYear W14687069312022 @default.
- W1468706931 crossrefType "journal-article" @default.
- W1468706931 hasAuthorship W1468706931A5004131447 @default.
- W1468706931 hasAuthorship W1468706931A5018794637 @default.
- W1468706931 hasAuthorship W1468706931A5088748837 @default.
- W1468706931 hasAuthorship W1468706931A5089441541 @default.
- W1468706931 hasAuthorship W1468706931A5090611425 @default.
- W1468706931 hasConcept C126322002 @default.
- W1468706931 hasConcept C185592680 @default.
- W1468706931 hasConcept C2777148285 @default.
- W1468706931 hasConcept C2779399885 @default.
- W1468706931 hasConcept C2780749602 @default.
- W1468706931 hasConcept C2780965833 @default.
- W1468706931 hasConcept C2781089062 @default.
- W1468706931 hasConcept C55493867 @default.
- W1468706931 hasConcept C71924100 @default.
- W1468706931 hasConceptScore W1468706931C126322002 @default.
- W1468706931 hasConceptScore W1468706931C185592680 @default.
- W1468706931 hasConceptScore W1468706931C2777148285 @default.
- W1468706931 hasConceptScore W1468706931C2779399885 @default.
- W1468706931 hasConceptScore W1468706931C2780749602 @default.
- W1468706931 hasConceptScore W1468706931C2780965833 @default.
- W1468706931 hasConceptScore W1468706931C2781089062 @default.
- W1468706931 hasConceptScore W1468706931C55493867 @default.
- W1468706931 hasConceptScore W1468706931C71924100 @default.
- W1468706931 hasIssue "3" @default.
- W1468706931 hasLocation W14687069311 @default.
- W1468706931 hasLocation W14687069312 @default.
- W1468706931 hasOpenAccess W1468706931 @default.
- W1468706931 hasPrimaryLocation W14687069311 @default.
- W1468706931 hasRelatedWork W2068634846 @default.
- W1468706931 hasRelatedWork W2071030966 @default.
- W1468706931 hasRelatedWork W2073922746 @default.
- W1468706931 hasRelatedWork W2104448829 @default.
- W1468706931 hasRelatedWork W2134132449 @default.
- W1468706931 hasRelatedWork W2147068566 @default.
- W1468706931 hasRelatedWork W2168975531 @default.
- W1468706931 hasRelatedWork W2322434720 @default.
- W1468706931 hasRelatedWork W2395983711 @default.
- W1468706931 hasRelatedWork W2885911850 @default.
- W1468706931 hasVolume "90" @default.
- W1468706931 isParatext "false" @default.
- W1468706931 isRetracted "false" @default.
- W1468706931 magId "1468706931" @default.
- W1468706931 workType "article" @default.