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- W1471171566 abstract "Publisher Summary This chapter presents frequency domain analysis methods, which are powerful tools for resolving the mechanisms of ion transport in epithelia. An overview of the basic features of the rabbit descending colon are provided. The ion transport properties of the mammalian colon provide numerous issues for investigators using frequency domain techniques. Results concerning potassium transport by this epithelium have been more controversial. A possible model for these transport systems is described. In choosing an appropriate equivalent-circuit model for the colon, two morphological features are taken into consideration: (1) the lateral intercellular space and (2) the crypt lumen. The dimensions of these parameters are important because a narrow or constricted intercellular space or crypt lumen is expected to have a relatively high electrical resistance. Initial attempts to fit the impedance data for the colon by a model, which ignores distributed resistance effects gave reasonable results. Moreover, use of a model, which includes the distributed effects caused by crypt lumen resistance (R p ) , greatly reduced the misfit of the theory to the data." @default.
- W1471171566 created "2016-06-24" @default.
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- W1471171566 date "1984-01-01" @default.
- W1471171566 modified "2023-09-27" @default.
- W1471171566 title "Chapter 4 Mechanisms of Ion Transport by the Mammalian Colon Revealed by Frequency Domain Analysis Techniques" @default.
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- W1471171566 doi "https://doi.org/10.1016/s0070-2161(08)60871-0" @default.
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