Matches in SemOpenAlex for { <https://semopenalex.org/work/W1473775923> ?p ?o ?g. }
- W1473775923 abstract "Receptors are defined as proteins that recognize a molecule or molecules (ligands) with some degree of specificity to initiate a biochemical signaling cascade that couples to secondary messenger systems. Receptor molecules transduce a signal from the exterior of the cell to the intracellular compartment, or reside within the cytosolic or nuclear compartment and convey signals that regulate gene expression. As such, receptor systems play critical roles in the regulation of development, cellular homeostasis, and disease onset and progression, to list a few. The ‘business end’ of virtually all receptor systems is often mediated by modulation of DNA functions and ultimately the regulation of protein/cellular functions. This article highlights major receptor systems that can be regulated by both endogenous and exogenous ligands, with a primary focus on xenobiotic receptor systems (XRSs) that modulate transcriptional events critical to the understanding the biology of the toxicological response. As appropriate, the molecular biology and human disease implications will be emphasized." @default.
- W1473775923 created "2016-06-24" @default.
- W1473775923 creator A5052485917 @default.
- W1473775923 creator A5068444084 @default.
- W1473775923 creator A5068717747 @default.
- W1473775923 date "2018-01-01" @default.
- W1473775923 modified "2023-09-26" @default.
- W1473775923 title "Overview of Receptor Systems" @default.
- W1473775923 cites W1565184863 @default.
- W1473775923 cites W160124365 @default.
- W1473775923 cites W1603640418 @default.
- W1473775923 cites W1822066871 @default.
- W1473775923 cites W1967071130 @default.
- W1473775923 cites W1968906511 @default.
- W1473775923 cites W1969816142 @default.
- W1473775923 cites W1970156844 @default.
- W1473775923 cites W1972158913 @default.
- W1473775923 cites W1975014056 @default.
- W1473775923 cites W1980814667 @default.
- W1473775923 cites W1987273882 @default.
- W1473775923 cites W1989612525 @default.
- W1473775923 cites W2002276902 @default.
- W1473775923 cites W2004009238 @default.
- W1473775923 cites W2004585452 @default.
- W1473775923 cites W2009222737 @default.
- W1473775923 cites W2011946509 @default.
- W1473775923 cites W2014754140 @default.
- W1473775923 cites W2017133589 @default.
- W1473775923 cites W2018328431 @default.
- W1473775923 cites W2020624387 @default.
- W1473775923 cites W2027057997 @default.
- W1473775923 cites W2033598745 @default.
- W1473775923 cites W2035226271 @default.
- W1473775923 cites W2036415863 @default.
- W1473775923 cites W2040843583 @default.
- W1473775923 cites W2041401980 @default.
- W1473775923 cites W2043586804 @default.
- W1473775923 cites W2045671770 @default.
- W1473775923 cites W2054114642 @default.
- W1473775923 cites W2064651444 @default.
- W1473775923 cites W2065157487 @default.
- W1473775923 cites W2070830789 @default.
- W1473775923 cites W2075250702 @default.
- W1473775923 cites W2079702648 @default.
- W1473775923 cites W2086510006 @default.
- W1473775923 cites W2086659744 @default.
- W1473775923 cites W2090939833 @default.
- W1473775923 cites W2091726431 @default.
- W1473775923 cites W2095427630 @default.
- W1473775923 cites W2099381688 @default.
- W1473775923 cites W2100193266 @default.
- W1473775923 cites W2131272120 @default.
- W1473775923 cites W2132185105 @default.
- W1473775923 cites W2137429553 @default.
- W1473775923 cites W2146687192 @default.
- W1473775923 cites W2146946155 @default.
- W1473775923 cites W2154532970 @default.
- W1473775923 cites W2160378721 @default.
- W1473775923 cites W2163212976 @default.
- W1473775923 cites W2164190691 @default.
- W1473775923 cites W2164837735 @default.
- W1473775923 cites W2165060628 @default.
- W1473775923 cites W2169378514 @default.
- W1473775923 cites W2170270785 @default.
- W1473775923 cites W2171885946 @default.
- W1473775923 cites W2315651913 @default.
- W1473775923 doi "https://doi.org/10.1016/b978-0-12-801238-3.01906-1" @default.
- W1473775923 hasPublicationYear "2018" @default.
- W1473775923 type Work @default.
- W1473775923 sameAs 1473775923 @default.
- W1473775923 citedByCount "2" @default.
- W1473775923 countsByYear W14737759232019 @default.
- W1473775923 crossrefType "book-chapter" @default.
- W1473775923 hasAuthorship W1473775923A5052485917 @default.
- W1473775923 hasAuthorship W1473775923A5068444084 @default.
- W1473775923 hasAuthorship W1473775923A5068717747 @default.
- W1473775923 hasConcept C104317684 @default.
- W1473775923 hasConcept C165864922 @default.
- W1473775923 hasConcept C170493617 @default.
- W1473775923 hasConcept C17971392 @default.
- W1473775923 hasConcept C201716435 @default.
- W1473775923 hasConcept C54355233 @default.
- W1473775923 hasConcept C62478195 @default.
- W1473775923 hasConcept C63932345 @default.
- W1473775923 hasConcept C71931279 @default.
- W1473775923 hasConcept C86339819 @default.
- W1473775923 hasConcept C86803240 @default.
- W1473775923 hasConcept C95444343 @default.
- W1473775923 hasConceptScore W1473775923C104317684 @default.
- W1473775923 hasConceptScore W1473775923C165864922 @default.
- W1473775923 hasConceptScore W1473775923C170493617 @default.
- W1473775923 hasConceptScore W1473775923C17971392 @default.
- W1473775923 hasConceptScore W1473775923C201716435 @default.
- W1473775923 hasConceptScore W1473775923C54355233 @default.
- W1473775923 hasConceptScore W1473775923C62478195 @default.
- W1473775923 hasConceptScore W1473775923C63932345 @default.
- W1473775923 hasConceptScore W1473775923C71931279 @default.
- W1473775923 hasConceptScore W1473775923C86339819 @default.
- W1473775923 hasConceptScore W1473775923C86803240 @default.
- W1473775923 hasConceptScore W1473775923C95444343 @default.