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- W147403299 abstract "Research Article1 February 1982free access Rapid and reversible disappearance of beta-adrenergic cell surface receptors. M. Staehelin M. Staehelin Search for more papers by this author P. Simons P. Simons Search for more papers by this author M. Staehelin M. Staehelin Search for more papers by this author P. Simons P. Simons Search for more papers by this author Author Information M. Staehelin and P. Simons The EMBO Journal (1982)1:187-190https://doi.org/10.1002/j.1460-2075.1982.tb01145.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The water soluble beta-adrenergic ligand [3H]CGP-12177 was used to measure the cell surface receptors in intact cells. In two cell lines, C6 glioma and WEHI 7 lymphoma cells, -50% of the cell surface receptors disappear within minutes of incubation of the cells with isoproterenol. The receptors can still be detected in homogenates and reappear on the cell surface when cells are washed and reincubated at 37 degrees C. The data agree with a disappearance of the receptors from the cell surface by an agonist-mediated endocytosis. Previous ArticleNext Article Volume 1Issue 21 February 1982In this issue RelatedDetailsLoading ..." @default.
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- W147403299 title "Rapid and reversible disappearance of beta-adrenergic cell surface receptors." @default.
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- W147403299 doi "https://doi.org/10.1002/j.1460-2075.1982.tb01145.x" @default.
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