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- W147656483 abstract "Vascular endothelial cells (EC) in vivo usually have a turnover measurable in years [1], however, they can be stimulated to proliferate much more rapidly, i.e., within 2–3 days, in response to injury or an angiogenic stimulus. The processes involved in capillary formation: (i) degradation of the existing basement membrane by metalloproteinases, (ii) migration of EC towards the angiogenic stimulus and (iii) proliferation of these EC to form the new capillary loops [2], are normally strictly regulated. However, a breakdown in the controlling mechanism is thought to be responsible for aberrant neovascularisation in solid tumor growth, rheumatoid arthritis, diabetic retinopathy and hypertension." @default.
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- W147656483 date "1992-01-01" @default.
- W147656483 modified "2023-09-25" @default.
- W147656483 title "A multichannel wounding device for the study of vascular repair in vitro" @default.
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- W147656483 doi "https://doi.org/10.1007/978-3-0348-7001-6_50" @default.
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