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- W147867285 abstract "Canalicular inflammation may lead to loss of compliance and stenosis, with lacrimal symptoms occurring despite anatomical patency.Microbial canaliculitis is frequently overlooked, leading to a delay in diagnosis and management.Failure adequately to remove canalicular stones and debris is a common cause for persistent canaliculitis.Canalicular epithelial inflammation due to primary herpes simplex infection is a common cause of canalicular, or common canalicular, occlusion.Subepithelial canalicular inflammation—as seen with lichen planus (LP)—may lead to a more severe and extensive annular fibrosis and carries a poor prognosis.Systemic chemotherapeutic agents, including radioiodine, 5-fluorouracil (5-FU), mitomycin C (MMC), and docetaxel, may injure the canalicular epithelium, the evidence suggesting active concentration of these agents by the lacrimal outflow structures.The surgical approach to canalicular occlusion depends on the extent of disease.Dacryocystorhinostomy (DCR) with retrograde canaliculostomy is the preferred surgery for proximal and midcanalicular occlusion.The indication for primary placement of a Jones canalicular bypass tube is the total absence of all distal canalicular and common canalicular structures, with this ascertained during open lacrimal surgery.The indication for secondary Jones tube placement is a functional failure after primary DCR with retrograde canaliculostomy.A canalicular bypass tube should be sutured such that the tube flange is held clear of the healing carunculectomy site; the function is not to prevent prolapse of the tube. As such, an encirclage suture is required only during primary placement of a bypass tube, when carunculectomy has just been performed." @default.
- W147867285 created "2016-06-24" @default.
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- W147867285 date "2010-01-01" @default.
- W147867285 modified "2023-09-25" @default.
- W147867285 title "Lacrimal Canalicular Inflammation and Occlusion: Diagnosis and Management" @default.
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- W147867285 doi "https://doi.org/10.1007/978-3-540-85542-2_4" @default.
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