Matches in SemOpenAlex for { <https://semopenalex.org/work/W1479757251> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1479757251 abstract "Publisher Summary Membrane fusion processes in cells underlie the structural integrity of the cytoplasm and are crucial to directing synthesis and export of enzymes, hormones, and transmitters. Export is accomplished by a process of exocytosis in which the membranes of secretory vesicles fuse with the plasma membrane. The fusion mechanism may involve a class of calcium-binding proteins termed “annexins.” This chapter discusses the annexin hypothesis for exocytosis. It focuses on function and molecular biology synexin (annexin VII) in secretory cells. Results from several laboratories have also shown that annexins I, II, and VII aggregate chromaffin granules and liposomes in vitro , and that annexin VII drives fusion of granule ghosts and liposomes. These data lend support to the hypothesis that these annexins may be secretory factors in vivo . The above mutagenesis experiments revealed the importance in annexin I of repeat one for aggregation activity and of repeats 2, 3, and 4 for calcium-binding sites. As all annexins bind to phospholipids in a calcium-dependent manner, membranes continue to be a focus for understanding annexin activity. Annexin II was detected in postpartum mammary epithelial cells, when calcium-dependent casein secretion starts and immunogold labeling of annexin VII in chromaffin cells was shown to decrease following treatment with a secretagogue. In addition, annexin II has been reported to insert into artificial membranes in the presence of calcium and to produce voltage-dependent channels." @default.
- W1479757251 created "2016-06-24" @default.
- W1479757251 creator A5003537359 @default.
- W1479757251 creator A5012125691 @default.
- W1479757251 date "1996-01-01" @default.
- W1479757251 modified "2023-09-23" @default.
- W1479757251 title "Annexin hypothesis for exocytosis" @default.
- W1479757251 cites W1526438718 @default.
- W1479757251 cites W1529736497 @default.
- W1479757251 cites W1530857641 @default.
- W1479757251 cites W1577860264 @default.
- W1479757251 cites W1581261085 @default.
- W1479757251 cites W1599931789 @default.
- W1479757251 cites W1619033851 @default.
- W1479757251 cites W1642525803 @default.
- W1479757251 cites W1669885839 @default.
- W1479757251 cites W1714325720 @default.
- W1479757251 cites W1883689801 @default.
- W1479757251 cites W1895561419 @default.
- W1479757251 cites W1970719668 @default.
- W1479757251 cites W2004744930 @default.
- W1479757251 cites W2009508312 @default.
- W1479757251 cites W2019270038 @default.
- W1479757251 cites W2029202268 @default.
- W1479757251 cites W2037328727 @default.
- W1479757251 cites W2040216242 @default.
- W1479757251 cites W2040618621 @default.
- W1479757251 cites W2045559042 @default.
- W1479757251 cites W2045783048 @default.
- W1479757251 cites W2048725327 @default.
- W1479757251 cites W2048862140 @default.
- W1479757251 cites W2085292543 @default.
- W1479757251 cites W2106463709 @default.
- W1479757251 cites W2120654193 @default.
- W1479757251 cites W2413435202 @default.
- W1479757251 doi "https://doi.org/10.1016/s1874-5342(96)80005-5" @default.
- W1479757251 hasPublicationYear "1996" @default.
- W1479757251 type Work @default.
- W1479757251 sameAs 1479757251 @default.
- W1479757251 citedByCount "0" @default.
- W1479757251 crossrefType "book-chapter" @default.
- W1479757251 hasAuthorship W1479757251A5003537359 @default.
- W1479757251 hasAuthorship W1479757251A5012125691 @default.
- W1479757251 hasConcept C103038307 @default.
- W1479757251 hasConcept C175969161 @default.
- W1479757251 hasConcept C178790620 @default.
- W1479757251 hasConcept C185592680 @default.
- W1479757251 hasConcept C202751555 @default.
- W1479757251 hasConcept C2780670749 @default.
- W1479757251 hasConcept C30345302 @default.
- W1479757251 hasConcept C41625074 @default.
- W1479757251 hasConcept C49039625 @default.
- W1479757251 hasConcept C519063684 @default.
- W1479757251 hasConcept C55493867 @default.
- W1479757251 hasConcept C86803240 @default.
- W1479757251 hasConcept C88634738 @default.
- W1479757251 hasConcept C95444343 @default.
- W1479757251 hasConceptScore W1479757251C103038307 @default.
- W1479757251 hasConceptScore W1479757251C175969161 @default.
- W1479757251 hasConceptScore W1479757251C178790620 @default.
- W1479757251 hasConceptScore W1479757251C185592680 @default.
- W1479757251 hasConceptScore W1479757251C202751555 @default.
- W1479757251 hasConceptScore W1479757251C2780670749 @default.
- W1479757251 hasConceptScore W1479757251C30345302 @default.
- W1479757251 hasConceptScore W1479757251C41625074 @default.
- W1479757251 hasConceptScore W1479757251C49039625 @default.
- W1479757251 hasConceptScore W1479757251C519063684 @default.
- W1479757251 hasConceptScore W1479757251C55493867 @default.
- W1479757251 hasConceptScore W1479757251C86803240 @default.
- W1479757251 hasConceptScore W1479757251C88634738 @default.
- W1479757251 hasConceptScore W1479757251C95444343 @default.
- W1479757251 hasLocation W14797572511 @default.
- W1479757251 hasOpenAccess W1479757251 @default.
- W1479757251 hasPrimaryLocation W14797572511 @default.
- W1479757251 hasRelatedWork W112704778 @default.
- W1479757251 hasRelatedWork W1968322238 @default.
- W1479757251 hasRelatedWork W1974215178 @default.
- W1479757251 hasRelatedWork W1985055612 @default.
- W1479757251 hasRelatedWork W1995087209 @default.
- W1479757251 hasRelatedWork W2008017834 @default.
- W1479757251 hasRelatedWork W2013274093 @default.
- W1479757251 hasRelatedWork W2017043638 @default.
- W1479757251 hasRelatedWork W2018725679 @default.
- W1479757251 hasRelatedWork W2033831238 @default.
- W1479757251 hasRelatedWork W2041330082 @default.
- W1479757251 hasRelatedWork W2055248999 @default.
- W1479757251 hasRelatedWork W2079162308 @default.
- W1479757251 hasRelatedWork W2083682484 @default.
- W1479757251 hasRelatedWork W2083762260 @default.
- W1479757251 hasRelatedWork W2153243435 @default.
- W1479757251 hasRelatedWork W2158937651 @default.
- W1479757251 hasRelatedWork W2284236061 @default.
- W1479757251 hasRelatedWork W2386789223 @default.
- W1479757251 hasRelatedWork W2405740562 @default.
- W1479757251 isParatext "false" @default.
- W1479757251 isRetracted "false" @default.
- W1479757251 magId "1479757251" @default.
- W1479757251 workType "book-chapter" @default.