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- W147981721 abstract "AM and CGRP receptors undergo differential intracellular receptor trafficking upon ligand stimulation. Intracellular trafficking of CLR/RAMP receptor complexes is regulated by posttranslational modifications and protein-protein interactions that differ for each cell type. Recent evidence is accumulating to suggest that the RAMP isoform in complex with CLR may play a role in determining the intracellular trafficking and fate of ligand-stimulated receptor complexes. In this chapter, we will review the current literature on mechanisms of regulating receptor trafficking and roles that have been demonstrated for RAMPs in this regulation." @default.
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- W147981721 date "2012-01-01" @default.
- W147981721 modified "2023-10-18" @default.
- W147981721 title "Regulation of GPCR Trafficking by RAMPs" @default.
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- W147981721 doi "https://doi.org/10.1007/978-1-4614-2364-5_3" @default.
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