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• W1480321196 abstract "Fibrinolysis plays a crucial role in the development of vascular disease. The interface between the plasminogen activators and inhibitors determines the fibrinolytic potential of human blood. In addition to fibrin degradation, fibrinolytic system components modulate several complex biological events such as angiogenesis, tumorigenesis, arteriosclerosis and cellular migration. Recent experimental and clinical data indicated that PAI-1 as a novel vascular risk factor. In this concise review, we will examine the accumulating evidence suggesting that there is an intricate relationship between these systems which may provide new therapeutic strategies for prevention of vascular disease." @default.
• W1480321196 created "2016-06-24" @default.
• W1480321196 creator A5052559996 @default.
• W1480321196 date "2005-01-27" @default.
• W1480321196 modified "2023-09-27" @default.
• W1480321196 title "Pivotal role of plasminogen-activator inhibitor 1 in vascular disease" @default.
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• W1480321196 doi "https://doi.org/10.1111/j.1742-1241.2005.00379.x" @default.
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