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- W1480879466 abstract "To the Editor: Two brain autopsy series of patients with Marfan syndrome have now been published1 2 and, in contrast to the conclusions drawn by Conway and colleagues,2 they strongly suggest that patients with Marfan syndrome are at an increased risk of harboring an intracranial aneurysm. Combining the 2 autopsy series, incidental intracranial aneurysms were found in 2 (6.5%) of 31 patients with Marfan syndrome.1 2 This could be compared with the 0.8% to 1.3% prevalence of incidental intracranial aneurysms in the general autopsy populations at the 2 institutions.1 2 However, the mean ages of the patients in the series with Marfan syndrome at autopsy were only 281 and 392 years, respectively, and intracranial aneurysms are now well recognized to be acquired lesions. The expected prevalence of incidental intracranial aneurysms in the third and fourth decades of life would be much lower. For example, in the Johns Hopkins autopsy study used by Conway and colleagues as representative of the general autopsy population, the prevalence of incidental …" @default.
- W1480879466 created "2016-06-24" @default.
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- W1480879466 date "1999-12-01" @default.
- W1480879466 modified "2023-10-16" @default.
- W1480879466 title "Marfan syndrome and intracranial aneurysms." @default.
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- W1480879466 doi "https://doi.org/10.1161/01.str.30.12.2759-g" @default.
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