FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1481187814> ?p ?o ?g. }

• W1481187814 endingPage "9" @default.
• W1481187814 startingPage "241" @default.
• W1481187814 abstract "Standardized aqueous extract of Neem (Azadirachta indica) leaves (AIE) has been reported to show both ulcer protective and ulcer healing effects in normal as well as in diabetic rats. To study the mechanism of its ulcer protective/healing actions, effects of AIE (500 mg/ kg) was studied on various parameters of offensive acid-pepsin secretion in 4 hr pylorus ligation, pentagastrin (PENTA, 5 microg/kg/hr)-stimulated acid secretion and gastric mucosal proton pump activity and defensive mucin secretion including life span of gastric mucosal cells in rats. AIE was found to inhibit acid-pepsin secretion in 4 hr pylorus ligated rats. Continuous infusion of PENTA significantly increased the acid secretion after 30 to 180 min or in the total 3 hr acid secretion in rat stomach perfusate while, AIE pretreatment significantly decreased them. AIE inhibited the rat gastric mucosal proton pump activity and the effect was comparable with that of omeprazole (OMZ). Further, AIE did not show any effect on mucin secretion though it enhanced life span of mucosal cells as evidenced by a decrease in cell shedding in the gastric juice. Thus, our present data suggest that the ulcer protective activity of AIE may be due to its anti-secretary and proton pump inhibitory activity rather than on defensive mucin secretion. Further, acute as well as sub acute toxicity studies have indicated no mortality with 2.5 g/kg dose of AIE in mice and no significant alterations in body or tissues weight, food and water intake, haematological profile and various liver and kidney function tests in rats when treated for 28 days with 1 g/kg dose of AIE." @default.
• W1481187814 created "2016-06-24" @default.
• W1481187814 creator A5001680148 @default.
• W1481187814 creator A5003386551 @default.
• W1481187814 creator A5037578229 @default.
• W1481187814 creator A5066145296 @default.
• W1481187814 creator A5071532716 @default.
• W1481187814 creator A5071989062 @default.
• W1481187814 date "2006-12-30" @default.
• W1481187814 modified "2023-09-26" @default.
• W1481187814 title "Effect of aqueous extract of neem (Azadirachta indica) leaves on offensive and diffensive gastric mucosal factors in rats." @default.
• W1481187814 cites W1015294589 @default.
• W1481187814 cites W12548334 @default.
• W1481187814 cites W146748053 @default.
• W1481187814 cites W1542845577 @default.
• W1481187814 cites W1570910952 @default.
• W1481187814 cites W1775749144 @default.
• W1481187814 cites W1993725555 @default.
• W1481187814 cites W1998116060 @default.
• W1481187814 cites W2002194801 @default.
• W1481187814 cites W2006598894 @default.
• W1481187814 cites W2023365015 @default.
• W1481187814 cites W2034868198 @default.
• W1481187814 cites W2036958200 @default.
• W1481187814 cites W2041179725 @default.
• W1481187814 cites W2055471110 @default.
• W1481187814 cites W2169713006 @default.
• W1481187814 cites W2206118544 @default.
• W1481187814 cites W2413472216 @default.
• W1481187814 cites W2414487335 @default.
• W1481187814 cites W2415173552 @default.
• W1481187814 cites W2416445129 @default.
• W1481187814 cites W92744961 @default.
• W1481187814 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17193895" @default.
• W1481187814 hasPublicationYear "2006" @default.
• W1481187814 type Work @default.
• W1481187814 sameAs 1481187814 @default.
• W1481187814 citedByCount "15" @default.
• W1481187814 countsByYear W14811878142012 @default.
• W1481187814 countsByYear W14811878142013 @default.
• W1481187814 countsByYear W14811878142014 @default.
• W1481187814 countsByYear W14811878142015 @default.
• W1481187814 countsByYear W14811878142018 @default.
• W1481187814 countsByYear W14811878142022 @default.
• W1481187814 crossrefType "journal-article" @default.
• W1481187814 hasAuthorship W1481187814A5001680148 @default.
• W1481187814 hasAuthorship W1481187814A5003386551 @default.
• W1481187814 hasAuthorship W1481187814A5037578229 @default.
• W1481187814 hasAuthorship W1481187814A5066145296 @default.
• W1481187814 hasAuthorship W1481187814A5071532716 @default.
• W1481187814 hasAuthorship W1481187814A5071989062 @default.
• W1481187814 hasConcept C126322002 @default.
• W1481187814 hasConcept C16311235 @default.
• W1481187814 hasConcept C179264091 @default.
• W1481187814 hasConcept C181199279 @default.
• W1481187814 hasConcept C185592680 @default.
• W1481187814 hasConcept C2777504413 @default.
• W1481187814 hasConcept C2778012502 @default.
• W1481187814 hasConcept C2779377912 @default.
• W1481187814 hasConcept C2779422922 @default.
• W1481187814 hasConcept C2781035296 @default.
• W1481187814 hasConcept C49039625 @default.
• W1481187814 hasConcept C55493867 @default.
• W1481187814 hasConcept C556039675 @default.
• W1481187814 hasConcept C71924100 @default.
• W1481187814 hasConcept C98274493 @default.
• W1481187814 hasConceptScore W1481187814C126322002 @default.
• W1481187814 hasConceptScore W1481187814C16311235 @default.
• W1481187814 hasConceptScore W1481187814C179264091 @default.
• W1481187814 hasConceptScore W1481187814C181199279 @default.
• W1481187814 hasConceptScore W1481187814C185592680 @default.
• W1481187814 hasConceptScore W1481187814C2777504413 @default.
• W1481187814 hasConceptScore W1481187814C2778012502 @default.
• W1481187814 hasConceptScore W1481187814C2779377912 @default.
• W1481187814 hasConceptScore W1481187814C2779422922 @default.
• W1481187814 hasConceptScore W1481187814C2781035296 @default.
• W1481187814 hasConceptScore W1481187814C49039625 @default.
• W1481187814 hasConceptScore W1481187814C55493867 @default.
• W1481187814 hasConceptScore W1481187814C556039675 @default.
• W1481187814 hasConceptScore W1481187814C71924100 @default.
• W1481187814 hasConceptScore W1481187814C98274493 @default.
• W1481187814 hasIssue "3" @default.
• W1481187814 hasLocation W14811878141 @default.
• W1481187814 hasOpenAccess W1481187814 @default.
• W1481187814 hasPrimaryLocation W14811878141 @default.
• W1481187814 hasRelatedWork W1481187814 @default.
• W1481187814 hasRelatedWork W1977997072 @default.
• W1481187814 hasRelatedWork W1999731440 @default.
• W1481187814 hasRelatedWork W2028680557 @default.
• W1481187814 hasRelatedWork W2155727937 @default.
• W1481187814 hasRelatedWork W2331600260 @default.
• W1481187814 hasRelatedWork W2414432370 @default.
• W1481187814 hasRelatedWork W2472585324 @default.
• W1481187814 hasRelatedWork W2785950598 @default.
• W1481187814 hasRelatedWork W4290358940 @default.
• W1481187814 hasVolume "50" @default.
• W1481187814 isParatext "false" @default.
• W1481187814 isRetracted "false" @default.

• next