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- W1481524976 abstract "Abstract An enzyme has been prepared from rat spleen which catalyzes the transfer of methyl groups from S-adenosylmethionine to cytosine moieties in DNA. This enzyme, which has been purified about 200-fold from the crude homogenate, differs from the known bacterial methylases in several ways, the most important of which is its apparent ability to methylate homologous DNA. The effect of heat denaturation upon the ability of DNA to accept methyl groups depends upon the source of the DNA. S-Adenosylethionine could not replace S-adenosylmethionine as a donor of ethyl groups in place of methyl groups." @default.
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- W1481524976 date "1969-03-01" @default.
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- W1481524976 title "The Purification and Properties of Deoxyribonucleic Acid Methylase from Rat Spleen" @default.
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- W1481524976 doi "https://doi.org/10.1016/s0021-9258(18)91823-5" @default.
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