FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1481836198> ?p ?o ?g. }

• W1481836198 endingPage "84" @default.
• W1481836198 startingPage "974" @default.
• W1481836198 abstract "In response to mission imperatives, transport aircrews must often sleep at inappropriate circadian times resulting in inadequate sleep. This study was undertaken to determine whether either melatonin or zopiclone could facilitate early circadian sleep, and to assess whether either of these medications would result in a psychomotor performance decrement which would preclude their use in aircrew.Thirteen subjects from DCIEM completed a double-blind cross-over protocol. All subjects were assessed for psychomotor performance during 3 drug conditions (placebo, 10 mg melatonin, and 7.5 mg zopiclone), which were separated by one week. Each of these conditions involved 2 nights of sleep, back-to-back, with the first night being a normal circadian control sleep (23:00 h bedtime, arising at 06:45 h), and the second night being an early circadian drug sleep (drugs at 16:45 h, 17:00 h bedtime, arising at 23:45 h). All subjects were tested for psychomotor performance, on both nights of each of the 3 drug conditions, pre- and post-sleep. Further, during the early circadian drug night, all subjects were tested every hour after arising at 23:45 h (24:00 h until 07:00 h. At the beginning of each psychomotor test session, subjects were asked for their subjective levels of sleepiness and fatigue.Relative to placebo (339.5 min) the subjects slept more on melatonin (370.2 min, p < 0.01), and zopiclone (373.3 min, p < 0.01). Performance in serial reaction time (SRT) task (p < 0.001), logical reasoning task (LRT) (p < 0.001), serial subtraction task (SST) (p < 0.02), and Multitask (MT) (p < 0.03) were impaired for all 3 drug conditions immediately on awakening, compared with pre-sleep performance, as a result of a sleep-inertia effect. With respect to the subjective data, sleep inertia effects were evident for sleepiness (p < 0.001), mental fatigue (p < 0.002), and physical fatigue (p < 0.05). For SRT, LRT, and SST, performance recovered to pre-sleep levels within 1.25 h of awakening, and for MT recovery occurred 2.25 h after awakening. There were no differences in performance or subjective measures between placebo, melatonin and zopiclone.Both zopiclone and melatonin improved sleep relative to placebo. After sleep inertia, performance recovered to pre-sleep levels for all tasks and was sustained at that level throughout the balance of the testing period. There was no impact of melatonin or zopiclone on performance measures compared with placebo." @default.
• W1481836198 created "2016-06-24" @default.
• W1481836198 creator A5034206633 @default.
• W1481836198 creator A5061889823 @default.
• W1481836198 creator A5067372822 @default.
• W1481836198 creator A5076615456 @default.
• W1481836198 creator A5084286778 @default.
• W1481836198 creator A5087020014 @default.
• W1481836198 creator A5089411815 @default.
• W1481836198 date "2001-11-01" @default.
• W1481836198 modified "2023-09-23" @default.
• W1481836198 title "Melatonin and zopiclone as pharmacologic aids to facilitate crew rest." @default.
• W1481836198 cites W105174322 @default.
• W1481836198 cites W1721092532 @default.
• W1481836198 cites W1827570073 @default.
• W1481836198 cites W1964161896 @default.
• W1481836198 cites W1983048388 @default.
• W1481836198 cites W1993381432 @default.
• W1481836198 cites W2001055430 @default.
• W1481836198 cites W2002716918 @default.
• W1481836198 cites W2010038812 @default.
• W1481836198 cites W2012867854 @default.
• W1481836198 cites W2013643340 @default.
• W1481836198 cites W2038305850 @default.
• W1481836198 cites W2047631147 @default.
• W1481836198 cites W2077768959 @default.
• W1481836198 cites W2081157905 @default.
• W1481836198 cites W2086516153 @default.
• W1481836198 cites W2089074779 @default.
• W1481836198 cites W2089868771 @default.
• W1481836198 cites W2138739388 @default.
• W1481836198 cites W2169506473 @default.
• W1481836198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11718517" @default.
• W1481836198 hasPublicationYear "2001" @default.
• W1481836198 type Work @default.
• W1481836198 sameAs 1481836198 @default.
• W1481836198 citedByCount "7" @default.
• W1481836198 countsByYear W14818361982016 @default.
• W1481836198 crossrefType "journal-article" @default.
• W1481836198 hasAuthorship W1481836198A5034206633 @default.
• W1481836198 hasAuthorship W1481836198A5061889823 @default.
• W1481836198 hasAuthorship W1481836198A5067372822 @default.
• W1481836198 hasAuthorship W1481836198A5076615456 @default.
• W1481836198 hasAuthorship W1481836198A5084286778 @default.
• W1481836198 hasAuthorship W1481836198A5087020014 @default.
• W1481836198 hasAuthorship W1481836198A5089411815 @default.
• W1481836198 hasConcept C118552586 @default.
• W1481836198 hasConcept C121446783 @default.
• W1481836198 hasConcept C126322002 @default.
• W1481836198 hasConcept C142724271 @default.
• W1481836198 hasConcept C15744967 @default.
• W1481836198 hasConcept C164953862 @default.
• W1481836198 hasConcept C169900460 @default.
• W1481836198 hasConcept C204787440 @default.
• W1481836198 hasConcept C27081682 @default.
• W1481836198 hasConcept C2777810057 @default.
• W1481836198 hasConcept C2778182776 @default.
• W1481836198 hasConcept C2778537899 @default.
• W1481836198 hasConcept C2780930544 @default.
• W1481836198 hasConcept C42219234 @default.
• W1481836198 hasConcept C71924100 @default.
• W1481836198 hasConceptScore W1481836198C118552586 @default.
• W1481836198 hasConceptScore W1481836198C121446783 @default.
• W1481836198 hasConceptScore W1481836198C126322002 @default.
• W1481836198 hasConceptScore W1481836198C142724271 @default.
• W1481836198 hasConceptScore W1481836198C15744967 @default.
• W1481836198 hasConceptScore W1481836198C164953862 @default.
• W1481836198 hasConceptScore W1481836198C169900460 @default.
• W1481836198 hasConceptScore W1481836198C204787440 @default.
• W1481836198 hasConceptScore W1481836198C27081682 @default.
• W1481836198 hasConceptScore W1481836198C2777810057 @default.
• W1481836198 hasConceptScore W1481836198C2778182776 @default.
• W1481836198 hasConceptScore W1481836198C2778537899 @default.
• W1481836198 hasConceptScore W1481836198C2780930544 @default.
• W1481836198 hasConceptScore W1481836198C42219234 @default.
• W1481836198 hasConceptScore W1481836198C71924100 @default.
• W1481836198 hasIssue "11" @default.
• W1481836198 hasLocation W14818361981 @default.
• W1481836198 hasOpenAccess W1481836198 @default.
• W1481836198 hasPrimaryLocation W14818361981 @default.
• W1481836198 hasRelatedWork W103820830 @default.
• W1481836198 hasRelatedWork W1481836198 @default.
• W1481836198 hasRelatedWork W1528543872 @default.
• W1481836198 hasRelatedWork W1969650486 @default.
• W1481836198 hasRelatedWork W2014069918 @default.
• W1481836198 hasRelatedWork W2024930363 @default.
• W1481836198 hasRelatedWork W2112565888 @default.
• W1481836198 hasRelatedWork W2160362483 @default.
• W1481836198 hasRelatedWork W2252484275 @default.
• W1481836198 hasRelatedWork W2731945390 @default.
• W1481836198 hasVolume "72" @default.
• W1481836198 isParatext "false" @default.
• W1481836198 isRetracted "false" @default.
• W1481836198 magId "1481836198" @default.
• W1481836198 workType "article" @default.