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- W148220675 abstract "A man aged 68 years with choledocholithiasis and cholangitis, with no clinical signs suggestive of acute pancreatitis and with a low excretion of amylase in the urine, showed persistent hyperamylasaemia which appeared to be caused by macroamylasaemia. The macroamylase (an IgA-lambda-amylase complex) accounted for nearly all (90%) of the amylase activity in the serum. The activity of pancreatic amylase in serum, determined by an immunoinhibition test which selectively blocks salivary amylase activity, constituted 99% of the amylase activity in serum (normal reference range 19-71). We showed, however, that complexed salivary amylase is not inhibited in the test, resulting in a falsely-increased activity of pancreatic amylase in serum. We conclude that macroamylasaemia can lead to a clinically misleading increase in the activity of pancreatic amylase in serum." @default.
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- W148220675 date "1990-09-01" @default.
- W148220675 modified "2023-09-23" @default.
- W148220675 title "[Misleadingly high amylase and pancreatic amylase activity in the plasma of patients with macroamylasemia]." @default.
- W148220675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1699137" @default.
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